DmeALTA0005497-2/2 @ dm6

FBgn0001248 | Idh

The gene Isocitrate dehydrogenase is referred to in FlyBase by the symbol DmelIdh (CG7176, FBgn0001248). It is a protein_coding_gene from Dmel. It has 10 annotated transcripts and 10 polypeptides (5 unique). Gene sequence location is 3L:8356404..8360906. Its molecular function is described by: magnesium ion binding; NAD binding; isocitrate dehydrogenase activity; isocitrate dehydrogenase (NADP+) activity. It is involved in the biological process described with: isocitrate metabolic process; oxidation-reduction process; NADP metabolic process; cellular response to oxidative stress. 38 alleles are reported. The phenotypes of these alleles manifest in: multi-tissue structure; organ system; cell; organism; multicellular structure. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; fertile; phenotype; flight defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.

• DmeALTA0005497-1/2
• DmeEX0004767
• DmeEX0004768
• DmeINT0021642