FBgn0001248 @ dm6
Biotype
protein_coding
Gene Symbol
Idh
Description
The gene Isocitrate dehydrogenase is referred to in FlyBase by the symbol DmelIdh (CG7176, FBgn0001248). It is a protein_coding_gene from Dmel. It has 10 annotated transcripts and 10 polypeptides (5 unique). Gene sequence location is 3L:8356404..8360906. Its molecular function is described by: magnesium ion binding; NAD binding; isocitrate dehydrogenase activity; isocitrate dehydrogenase (NADP+) activity. It is involved in the biological process described with: isocitrate metabolic process; oxidation-reduction process; NADP metabolic process; cellular response to oxidative stress. 38 alleles are reported. The phenotypes of these alleles manifest in: multi-tissue structure; organ system; cell; organism; multicellular structure. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; fertile; phenotype; flight defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
Coordinates
chr3L:8356404-8360906:-
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
EVENTS AND AS PROFILES[edit]
Associated events[edit]
Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Orthologous genes[edit]
Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
---|---|---|---|---|
Human | hg38 | ENSG00000138413 | IDH1 | 1-to-1 |
Human | hg19 | ENSG00000138413 | IDH1 | 1-to-1 |
Mouse | mm10 | ENSMUSG00000025950 | Idh1 | 1-to-1 |
Mouse | mm9 | ENSMUSG00000025950 | Idh1 | 1-to-1 |
Rat | rn6 | ENSRNOG00000015020 | Idh1 | 1-to-1 |
Cow | bosTau6 | ENSBTAG00000020527 | IDH1 | 1-to-1 |
Chicken | galGal4 | ENSGALG00000008818 | IDH1 | 1-to-1 |
Chicken | galGal3 | ENSGALG00000008818 | F1NPG2_CHICK | 1-to-1 |
Zebrafish | danRer10 | ENSDARG00000025375 | idh1 | 1-to-1 |