Special

FBgn0001248 @ dm6

Biotype
protein_coding
Gene Symbol
Idh
Description
The gene Isocitrate dehydrogenase is referred to in FlyBase by the symbol DmelIdh (CG7176, FBgn0001248). It is a protein_coding_gene from Dmel. It has 10 annotated transcripts and 10 polypeptides (5 unique). Gene sequence location is 3L:8356404..8360906. Its molecular function is described by: magnesium ion binding; NAD binding; isocitrate dehydrogenase activity; isocitrate dehydrogenase (NADP+) activity. It is involved in the biological process described with: isocitrate metabolic process; oxidation-reduction process; NADP metabolic process; cellular response to oxidative stress. 38 alleles are reported. The phenotypes of these alleles manifest in: multi-tissue structure; organ system; cell; organism; multicellular structure. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; fertile; phenotype; flight defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
Coordinates
chr3L:8356404-8360906:-
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Alternative 3'ss
0
NA
-
92.16
84.75
0
Alternative 3'ss
30
chr3L:8357906-8357935
-
7.84
84.75
0
Exon Skipping
160
chr3L:8358556-8358715
-
17.48
78.64
0
Exon Skipping
57
chr3L:8358016-8358072
-
7.06
80.27
0
Intron Retention
2887
chr3L:8357906-8360792
-
6.88
79.1
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000138413 IDH1 1-to-1
Human hg19 ENSG00000138413 IDH1 1-to-1
Mouse mm10 ENSMUSG00000025950 Idh1 1-to-1
Mouse mm9 ENSMUSG00000025950 Idh1 1-to-1
Rat rn6 ENSRNOG00000015020 Idh1 1-to-1
Cow bosTau6 ENSBTAG00000020527 IDH1 1-to-1
Chicken galGal4 ENSGALG00000008818 IDH1 1-to-1
Chicken galGal3 ENSGALG00000008818 F1NPG2_CHICK 1-to-1
Zebrafish danRer10 ENSDARG00000025375 idh1 1-to-1