DmeALTA0008061-4/4 @ dm6
Alternative 3'ss
Gene
FBgn0000535 | eag
Description
The gene ether a go-go is referred to in FlyBase by the symbol Dmeleag (CG10952, FBgn0000535). It is a protein_coding_gene from Dmel. It has 8 annotated transcripts and 8 polypeptides (7 unique). Gene sequence location is X:14955477..15009989. Its molecular function is described by: voltage-gated cation channel activity; voltage-gated potassium channel activity; ion channel binding. It is involved in the biological process described with 11 unique terms, many of which group under: cognition; behavior; multicellular organismal process; learning or memory; transport. 31 alleles are reported. The phenotypes of these alleles manifest in: cytoplasm; organelle; nervous system; myofibril; cellular anatomical entity. The phenotypic classes of alleles include: mating defective; phenotype; sensory perception defective; behavior defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed during late larval stages, during early pupal stages.
Coordinates
chrX:15000413-15002402:+
Coord C1 exon
chrX:15000413-15000828
Coord A exon
chrX:15002112-15002158
Coord C2 exon
chrX:15002159-15002402
Length
47 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGT
5' ss Score
10.47
3' ss Seq
AATGCAACAACATATACAAGAAG
3' ss Score
-6.07
Exon sequences
Seq C1 exon
GCAAGGGCGACGTCTTCGGCGATCAATTCTGGAAGGACTCGGCCGTTGGCCAGAGTGCGGCCAATGTGCGTGCTCTGACCTATTGTGATTTGCATGCCATCAAACGTGATAAATTGCTCGAAGTCCTCGATTTCTATTCGGCATTTGCGAATAGCTTTGCACGCAATCTGGTGCTCACCTACAATCTCAGACATCGACTGATTTTTCGCAAGGTGGCCGATGTGAAGCGCGAAAAAGAATTGGCCGAACGGCGTAAGAACGAGCCGCAATTGCCCCAGAATCAGGACCATCTCGTCCGGAAGATCTTCTCCAAATTTCGTCGCACTCCGCAGGTCCAAGCGGGCAGTAAGGAGCTCGTCGGCGGTTCCGGCCAAAGTGATGTCGAGAAGGGTGACGGCGAGGTGGAGCGAACTAAG
Seq A exon
AAGCTACCAGCCAAACTGACACTGACCGAGGACGCTCGCATCCTTAG
Seq C2 exon
CACCGCCGCGGCGCCCTCGCCATCGCCATCCCCATCGCCCTCATCGGGTCCACCATCTGCGCGCAGTACACGGGCCAGCAAGTGGGGACGCCTCCTGGGCAGTTCAAGCGTCGATTCAGCTAGCGACACCAGCGCCAAGGTAGCCGTCTCGAGAAGTTTGAGCGCCCGCGAAAGCCTCCGAGAGAGCACCGCCCAAGCGCGGCAGAGTAGTACTTCGAGTAGCAATGGTGGACAAGGCAACAAA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0000535-20-26,20-25,20-24,20-23-4/4
Average complexity
Alt3
Mappability confidence:
NA
Protein Impact
Protein isoform when splice site is used (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.308 A=NA C2=0.953
Domain overlap (PFAM):
C1:
PF0002724=cNMP_binding=PD(54.7=33.8)
A:
NA
C2:
NO
Main Inclusion Isoform:
FBpp0301719
Main Skipping Isoform:
FBpp0110308
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0292378
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCGAGGTGGAGCGAACTAAG
R:
GCTAGCTGAATCGACGCTTGA
Band lengths:
144-191
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)