Special

FBgn0000535 @ dm6

Biotype
protein_coding
Gene Symbol
eag
Description
The gene ether a go-go is referred to in FlyBase by the symbol Dmeleag (CG10952, FBgn0000535). It is a protein_coding_gene from Dmel. It has 8 annotated transcripts and 8 polypeptides (7 unique). Gene sequence location is X:14955477..15009989. Its molecular function is described by: voltage-gated cation channel activity; voltage-gated potassium channel activity; ion channel binding. It is involved in the biological process described with 11 unique terms, many of which group under: cognition; behavior; multicellular organismal process; learning or memory; transport. 31 alleles are reported. The phenotypes of these alleles manifest in: cytoplasm; organelle; nervous system; myofibril; cellular anatomical entity. The phenotypic classes of alleles include: mating defective; phenotype; sensory perception defective; behavior defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed during late larval stages, during early pupal stages.
Coordinates
chrX:14955477-15009989:+
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Alternative 3'ss
44
chrX:15002115-15002158
+
59.25
82.34
0
Alternative 3'ss
47
chrX:15002112-15002158
+
39.48
79.72
0
Alternative 3'ss
0
NA
+
22.27
53.83
0
Alternative 3'ss
6
chrX:14993446-14993451
+
73.81
63.01
0
Alternative 5'ss
0
NA
+
34.93
58.54
0
Alternative 5'ss
6
chrX:14986394-14986399
+
65.07
58.54
0
Exon Skipping
51
chrX:14991346-14991396
+
23.26
94.87
0
Exon Skipping
291
chrX:15002112-15002402
+
68.34
90.21
0
Exon Skipping
18
chrX:15003161-15003178
+
31.67
83.79
0
Intron Retention
1227
chrX:14996707-14997933
+
17.63
46.66
0
Intron Retention
1724
chrX:14998134-14999857
+
22.52
96.48
0
Intron Retention
302
chrX:15000111-15000412
+
11.2
46.03
0
Intron Retention
3206
chrX:15000829-15004034
+
34.97
94.12
0
Intron Retention
3920
chrX:14986400-14990319
+
12.5
32.66
0
Intron Retention
1323
chrX:14991397-14992719
+
15.22
82.99
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000140015 KCNH5 1-to-2
Human hg19 ENSG00000140015 KCNH5 1-to-2
Human hg19 ENSG00000143473 KCNH1 1-to-2
Mouse mm10 ENSMUSG00000034402 Kcnh5 1-to-2
Mouse mm10 ENSMUSG00000058248 Kcnh1 1-to-2
Mouse mm9 ENSMUSG00000034402 Kcnh5 1-to-2
Mouse mm9 ENSMUSG00000058248 Kcnh1 1-to-2
Rat rn6 ENSRNOG00000003841 Kcnh1 1-to-2
Rat rn6 ENSRNOG00000009542 Kcnh5 1-to-2
Cow bosTau6 ENSBTAG00000008710 KCNH1 1-to-2
Cow bosTau6 ENSBTAG00000011379 KCNH5 1-to-2
Chicken galGal4 ENSGALG00000009877 KCNH1 1-to-2
Chicken galGal4 ENSGALG00000011858 KCNH5 1-to-2
Chicken galGal3 ENSGALG00000009877 KCNH1 1-to-2
Chicken galGal3 ENSGALG00000011858 KCNH5 1-to-2
Zebrafish danRer10 ENSDARG00000023236 kcnh1b 1-to-4
Zebrafish danRer10 ENSDARG00000024167 kcnh1a 1-to-4
Zebrafish danRer10 ENSDARG00000043220 kcnh5a 1-to-4
Zebrafish danRer10 ENSDARG00000069117 kcnh5b 1-to-4