DmeEX0000576 @ dm6
Exon Skipping
Gene
FBgn0031835 | CG11319
Description
This gene is referred to in FlyBase by the symbol DmelCG11319 (FBgn0031835). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2L:6568400..6601068. Its molecular function is described by: serine-type peptidase activity. It is involved in the biological process described with: proteolysis. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.
Coordinates
chr2L:6572196-6580510:-
Coord C1 exon
chr2L:6580415-6580510
Coord A exon
chr2L:6577653-6577780
Coord C2 exon
chr2L:6572196-6572542
Length
128 bp
Sequences
Splice sites
3' ss Seq
GCTCCACTTGCCCCACACAGAAA
3' ss Score
5.24
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
Exon sequences
Seq C1 exon
TTGGTCTCCAGCAATCCCAACCAACGGAACTGGCGCGGAATTCTCATCGCGCTGCTGGTCATCATCATTGTGCTGGCCCTGATTGTTACATCGGTG
Seq A exon
AAAACCCTGTCACCCTTCACCTTCACCATATCGGCGGACAAGCGCTATCTGCTTCTGGCCCAGAATGTTGTGAAACTATTCCGGCACTCGTACTTGGCCCAGTACACGCTCTACGACATTCAGACCAG
Seq C2 exon
GTGCCGCCGGAGTCGAAAGCTGGTCTTGGCAATGGCGGCGATATGCAACAGCAATAAACTTAAATTATGGCAGCAGAAAATTCTGATAACAAAAGTATGGAACACAACAAACTTCAACCGGAACGTGCGAACGAAATGTTTTTCTGTAAATTGCATTCAATGTGATTTATCATGAACACACCCACGACACTCACATACACAGCAAGCGGCTAAATGGCAACTCAAATAGCCAAACGGCGGCGGCGACGGCAAAAAAAGCAACAACTAAGTTAAATGGCATTTTGTGTAAAATTAATAAGCAAAGCAGCAGCAGCAGCAGCAGCGAAATGCGAAATGCGAAATGCCAA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0031835_MULTIEX1-3/12=C1-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.094 A=0.000 C2=0.667
Domain overlap (PFAM):
C1:
PF059157=DUF872=FE(44.3=100)
A:
PF0093016=DPPIV_N=PU(8.2=74.4)
C2:
NO
Main Inclusion Isoform:
FBpp0088584
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0309854, FBpp0309855
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCATCATCATTGTGCTGGCCC
R:
CCGCTTGCTGTGTATGTGAGT
Band lengths:
247-375
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)