Special

DmeINT0002416 @ dm6

Intron Retention

Gene
FBgn0031835 | CG11319
Description
This gene is referred to in FlyBase by the symbol DmelCG11319 (FBgn0031835). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2L:6568400..6601068. Its molecular function is described by: serine-type peptidase activity. It is involved in the biological process described with: proteolysis. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.
Coordinates
chr2L:6577378-6577780:-
Coord C1 exon
chr2L:6577653-6577780
Coord A exon
chr2L:6577590-6577652
Coord C2 exon
chr2L:6577378-6577589
Length
63 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
3' ss Seq
GCGACCCTAATCCCCGACAGCGA
3' ss Score
3.76
Exon sequences
Seq C1 exon
AAAACCCTGTCACCCTTCACCTTCACCATATCGGCGGACAAGCGCTATCTGCTTCTGGCCCAGAATGTTGTGAAACTATTCCGGCACTCGTACTTGGCCCAGTACACGCTCTACGACATTCAGACCAG
Seq A exon
GTGAGTTCTGGCATCATTCCGCAGCCGTCCACACTTTAGCATTGCGACCCTAATCCCCGACAG
Seq C2 exon
CGAGAGCATCAAGCTGCGCCACAGTCCGCACCAGGATGAATGGCCATACCTGCACTACGCACGATTTACGCCAGCTGGAAACGCACTGGTCTGGGTCCAGAGCTACGATATCTATTACCGAGAGGAGGTCCGCAGTGCGTCCGTGCATCGGATTACCCACGATGCGGTGCCCGGAGTGGTGTACAACGGCATTCCCGATTGGCTGTACGAAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0031835:FBtr0089641:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact

ORF disruption upon sequence inclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):

C1:
PF0093016=DPPIV_N=PU(8.2=74.4)
A:
NA
C2:
PF0093016=DPPIV_N=FE(18.2=100)


Main Inclusion Isoform:
NA


Main Skipping Isoform:
FBpp0309854


Other Inclusion Isoforms:
NA


Other Skipping Isoforms:
FBpp0088584, FBpp0309855
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACAAGCGCTATCTGCTTCTGG
R:
CATTCATCCTGGTGCGGACTG
Band lengths:
133-196
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)