Special

DmeEX0000580 @ dm6

Exon Skipping

Gene
FBgn0031835 | CG11319
Description
This gene is referred to in FlyBase by the symbol DmelCG11319 (FBgn0031835). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2L:6568400..6601068. Its molecular function is described by: serine-type peptidase activity. It is involved in the biological process described with: proteolysis. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.
Coordinates
chr2L:6572196-6580510:-
Coord C1 exon
chr2L:6580415-6580510
Coord A exon
chr2L:6576041-6576164
Coord C2 exon
chr2L:6572196-6572542
Length
124 bp
Sequences
Splice sites
3' ss Seq
CGAATCATTCTAACCCACAGAGA
3' ss Score
6.15
5' ss Seq
GAGGTGAGT
5' ss Score
10.03
Exon sequences
Seq C1 exon
TTGGTCTCCAGCAATCCCAACCAACGGAACTGGCGCGGAATTCTCATCGCGCTGCTGGTCATCATCATTGTGCTGGCCCTGATTGTTACATCGGTG
Seq A exon
AGATCACTACTTCAGCAGTGCCAGTTGGGTGAGTCACTCGAAGATCGCGGTGGTGTGGCTAAATCGTCCGCAAAACATCTCGGTGGTCAGTGTGTGTAAGGCTCCATTGTTCCAGTGCATCGAG
Seq C2 exon
GTGCCGCCGGAGTCGAAAGCTGGTCTTGGCAATGGCGGCGATATGCAACAGCAATAAACTTAAATTATGGCAGCAGAAAATTCTGATAACAAAAGTATGGAACACAACAAACTTCAACCGGAACGTGCGAACGAAATGTTTTTCTGTAAATTGCATTCAATGTGATTTATCATGAACACACCCACGACACTCACATACACAGCAAGCGGCTAAATGGCAACTCAAATAGCCAAACGGCGGCGGCGACGGCAAAAAAAGCAACAACTAAGTTAAATGGCATTTTGTGTAAAATTAATAAGCAAAGCAGCAGCAGCAGCAGCAGCGAAATGCGAAATGCGAAATGCCAA
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0031835_MULTIEX1-7/12=C1-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.094 A=0.000 C2=0.667
Domain overlap (PFAM):

C1:
PF059157=DUF872=FE(44.3=100)
A:
PF0093016=DPPIV_N=FE(10.5=100)
C2:
NO


Main Inclusion Isoform:
FBpp0088584


Main Skipping Isoform:
NA


Other Inclusion Isoforms:
FBpp0309854, FBpp0309855


Other Skipping Isoforms:
NA
Primers PCR
Suggestions for RT-PCR validation
F:
TCATCATCATTGTGCTGGCCC
R:
CCGCTTGCTGTGTATGTGAGT
Band lengths:
247-371
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)