DmeEX6016874 @ dm6
Exon Skipping
Gene
FBgn0261722 | fwe
Description
The gene flower is referred to in FlyBase by the symbol Dmelfwe (CG6151, FBgn0261722). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3L:15810081..15816410. Its molecular function is described by: calcium channel activity. It is involved in the biological process described with 10 unique terms, many of which group under: programmed cell death; chemical homeostasis; neuron apoptotic process; regulation of apoptotic process; cation transport. 39 alleles are reported. The phenotypes of these alleles manifest in: tergum; egg chamber; cellular anatomical entity; larval thorax; visual system. The phenotypic classes of alleles include: phenotype; increased mortality; endocytosis defective; some die during larval stage.
Coordinates
chr3L:15810081-15813353:-
Coord C1 exon
chr3L:15813246-15813353
Coord A exon
chr3L:15811220-15812897
Coord C2 exon
chr3L:15810081-15810848
Length
1678 bp
Sequences
Splice sites
3' ss Seq
AACTATAAACTAACACGTAGAGC
3' ss Score
1.43
5' ss Seq
CAGGCAAAT
5' ss Score
1.01
Exon sequences
Seq C1 exon
CATGGCCATTCCGCCCATTATTCTGTGCTTTGGACTGGCCAGCTTATTCGGCAGTGGGCTGATCTTTGGCACTGGCGTGGTTTACGGCATGATGGCGTTAGGCAAGAA
Seq A exon
AGCTTCTCGAGAGGACATGGCCGCCGCTGCCACATCGCCCACACAGATGGCCGGCAGTCAGGCGGGCGGTCAGATGCAGATGGGCGGCGATCAGCATATCACACTCATGGAAGACCCCGATGTCTGGCGCCCCACATAAATTCCTAGCCGCGCCATTAGTAACTGCCAAAAAACCACACTCAGATACAGATAAAGACACAGATACTCAGATACACAGATTCACACACAAAATACTCCACTAGAAATGCGAACGATGCAAGAATTGATCGAGTAACAAATATTTTACGGCGCCTAGTTTTTAGTGTTCGTTCCGAGGATAAATGCAACTAAGTGAAAAGGAAAATCACTACAAAGCAGCATTGTAGGGCATCAGAGAACTAGTATACAGAACACCCCACCAAATACAAAAGAAAATTTAACGAAATTCTCATTACTGTTGAAACCGAGAGTGTTAGTAATCAAAGTATATTTTGGGCAAATGCATTTCCGTCATTCGACCCCCCGTTTTGCATGGCATTCGTACTATATTCGTATTCAAATTTTTTAATATCTTTCGTCGAGCGGTTGGTGTTGTTAAGAACTACAGTTAAATATATATAATATGCATAGAACAACTACTGATAACAATAACGTAACTCACATGTCAAACTCTGCAGCAAGCATATATTTTTAGTGAGAAACTATATTTGAAAGCTAACCGAATGCAAGAGGAACCGGAACCTATAAGTTAACCACAGCTTCCACACACTCACACACAGCTAATGCTAATGGAAAGCCACTGATGATATGGACAAGTGAATGTCGAGAACCTAGAGCAATATGTACAACTCAGAAATAATTAACTTTATATGCTTTGCTTCGATGTAAACCATAAAATTAAATGTTAAACGTTATTTGAGAATCGATTTGCTCGCGGGATAGTCACAATTTGAAATTGAACATAATCAAGCATACAGATAGAATATATATATATATATATATATACAACAAGTTGAGAATTTACCAGTTATATTTTTTAAATGTTGTAACCGAAAAGTGTCCATTTCAATTTGATGCATTGTTAGACGGTTTTCTTTTTAGACAATTACTTGGTTAATAGGATTTCGTTTTCGGGTTTCGTATGATTTCTTGTTTGCTAGAAGTATATGCTTATTTTTTTTAGTATACCTAAGTTATTTATAAGAGTTTATTCCAATCGTTTAACTTTGAAAGTCTGAGAAAAACGTTTTAAATTATTTTTGTTGTTGCCTATTGGCATTCTTACCACAGAAGCATTCCAAAATCTGTTTACTTTACGCATAAGTTATTGTATAGTTTAATTATTATAACTTTAAATATACATTATTTACAAGAAACTCGCGATAATTTATTACAATTTAGCCTTCGCCAGCAACTAAGAGTCTCACCTAAAGTAATCACGAATCATAATTAATTTGTTGAACTTTGTTAATCAATGAACGCAACACTAAAAATGAAAACATAAACATGTAAAATATTTCGTTAGAATTTGAACGCGCATGATTCAAATATCAAACACTTTGTACATGCCACCTGAAAACTGTCCAAAATCCTGCCGTTAAAGCCAAGTACATTCAACGACGGCCAACAGCGATTAACAACAATATACGATTTACGTTAACGAGTTCTGAACTTTGCTGCGTCCAAGAGATCACTACAG
Seq C2 exon
AGCATCCGCCGAGGACATGCGGGCAGCTGCTCAGCAAACCTTCGGAGGAAACACACCTGCCCAAACCAACGATCGAGCGGGGATTGTGAACAACGCCCAGCCCTTCTCCTTCACCGGTGCCGTGGGCACGGACAGCAATGTGTGATTCAGAAGCTAGCTGATCGGGATTTCGAGGAATCGAAGAGCTGGGTGTGCCGTGAGAAAACAAGACTCAAAACGCAACATTTGAAGGGCAAACCTAACCAAGAGAACATCGGCAGGCAATCATAAACATAATCATGTGCAATTTCTGATTGTTCAATAACCAACGCAAATGGATAACAAAAGTTTTTAAATCCGATTAGCTCTGATCTCTTTCTAGAGCAATCCAAATTACTCGATCAGAAAGAAGCCACCCAAAACAAGATCATTAAATTTTAAACCATTTTTGTATTAAATGTATGTAAATGTATATTGGTTTTAAAAGCGTTTTGCGTTTTCTGTATCCTATTAATTAATTG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0261722-'13-10,'13-6,17-10=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.085 C2=0.042
Domain overlap (PFAM):
C1:
PF102334=Cg6151-P=FE(31.9=100)
A:
PF102334=Cg6151-P=PD(0.1=0.0)
C2:
PF102334=Cg6151-P=PD(0.1=0.0)
Main Inclusion Isoform:
FBpp0075296
Main Skipping Isoform:
FBpp0075297
Other Inclusion Isoforms:
FBpp0075298
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Chicken
(galGal3)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATTCTGTGCTTTGGACTGGCC
R:
TGATTGCCTGCCGATGTTCTC
Band lengths:
356-2034
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)