DreEX0055520 @ danRer10
Exon Skipping
Gene
ENSDARG00000060841 | pik3c2a
Description
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha [Source:ZFIN;Acc:ZDB-GENE-030328-39]
Coordinates
chr18:27018737-27039900:+
Coord C1 exon
chr18:27018737-27018792
Coord A exon
chr18:27024823-27025954
Coord C2 exon
chr18:27039800-27039900
Length
1132 bp
Sequences
Splice sites
3' ss Seq
CTCTCAATTTTCTCTCATAGGCA
3' ss Score
10.7
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
Exon sequences
Seq C1 exon
AGCAAATTTTCCAGCTGGAGGAAAATGTCCAGCGTCAAAGATCGGAGAGTCTGAAG
Seq A exon
GCACCTGTTGTAAAGTTCCCATCAGAACCCAGTGGTCTCCTCATGTACATCGCAAGGCAGAGCTGACACCATGGCCCACATATCCAGTGGCAATGGGTTTAAGTTTGACAGGCCAGCCTCTCCGGGGGTGGTCCGGCCAAAAGGAATTGTGGGGAAGGAAGAGGCTTTACGCATGGAGGTAGAGGCCTTCGATAAAATTAAGCGCGAGAAAAGGCACACACTCCCAGTCACAGCCTCTTCTGTTAATCCCCTTCCCAATCCAACAGCGCAAACATCCAGCAGCCGGCCAGAGAAAGACCTTATTGTATTCTGCGAATCAGAAACACAGAAGAAGGAGCAAAAAGACAACTTTGAGGACATCGATTTGGAGAACCTGACAAAGGAGGAGCTGGAAAAGCTGCTTCTGGATGACAGTTTTGGTGCAAACAAAATGACAAGACCTTCCTCTTTGCTAGGTTGCAATCTCAGCGCATCATATCCTGGCGGACATGCCTTCAACCCCTCTTCGTTCCACTGGACACCCACTCCAACGCATGCACAGACTCCCATCTTCCCCTCTGCTCCATTCGCCAAGCCTCCTTGCTCTTTCCAGAATGGCTTTAGTCCAGCAATGTCTCCATTTATTCCACCGACCCCCTTTCTCTCCTTTACTCCCATCCAACCACCTGCTGCTCTGGTCTACTCGCAGCCTGCCGTCACCCCAGAGATGGCCAAGCTGTTTGACAAGATTGCCAGCACTTCGGAATACTTGAAGAACGGCAGGTCCTCTAGCATGGAAACCGAATCGGCAAGTGTCAAGTCTCTGGAGCCCCTACCTCTGCCCTCAGAACCTCCTAACATCAGCCGATTTGAATGGCTGGACTTGGACCCTCTCAACAAGCGCAAGGAGGTGGAGGTCGAGGAGACACCTGCTGTTTCAAGCTGTCCTTTTATTGAGGAGTCTGGGAAAGCTAAAGACCCGTGGGATGCGGTTCTTCAGGATGAGCATGAAACTGTAGATAATGGCAGTCCCACCGCAGAGGAAAAGAGCAAGGCAACTCAACCCAGAAGAGCATCCACAGGGGCGGCTGTAACAAAAAGCCAATCCCTCAGTATATCTGCAAACTCAACGAATCAAAGCACAGGCAAACAG
Seq C2 exon
GTCAATAAGGGAAGCACAAATGTACTGTCCAAGTACTCTGCCTTACAGGAGAAGGAAGCCCAGAATCTAGAAGTTGTAGCATTCTGTGAAGACATTTCAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000060841_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion (Ref, Alt. ATG (<=10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.579 C2=0.147
Domain overlap (PFAM):
C1:
NA
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 1 annotated functions for this event
PMID: 12719431
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, de novo protein sequencing by mass spectrometry, electrophoretic mobility supershift assay, inhibitor, protein kinase assay, western blot. ELM ID: ELMI003240; ELM sequence: LQVSPK; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]