DreEX0061774 @ danRer10
Exon Skipping
Gene
ENSDARG00000042833 | rffl
Description
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-040426-2274]
Coordinates
chr15:4568992-4587803:-
Coord C1 exon
chr15:4587738-4587803
Coord A exon
chr15:4576742-4576930
Coord C2 exon
chr15:4568992-4569375
Length
189 bp
Sequences
Splice sites
3' ss Seq
TTTCCCTGTGTGTTTTCCAGTAG
3' ss Score
10.25
5' ss Seq
AAGGTAATC
5' ss Score
7.46
Exon sequences
Seq C1 exon
ATGGCAAAGGCTTGGACTTTATATCCTTGAACGTCACAGTTTACAAGACACTGAGTCACTGTCAAG
Seq A exon
TAGGTGTGGAGCATGTGGGCCAGCTGCTGCGGCTGGCTATGTCTGGATGATTCCAGTATGGAAGACACCAGAGGAAGCCAACAGCGCCAGGCCTTCACGAACTCAGGCTTCAGCAGTTACCCGTCTCCCACTGCACCAGAACACACATGCAAGTCCTGTGGAGGTCGCTTCGACAGTTTAACCAGGAAG
Seq C2 exon
CACGTGTGCATGGACTGCAAGAAGAGCTACTGCAGCCAGTGCTCCACTCAGCAGGAGCTCCAGCCGTGGCTGTGCCGCACCTGCCAGCGTTTCCGCGGCATCTTGTTGGAGCGAGCAGAACTCATGAAGCTCAAGGTGAAGGATCTCAGGGACTACCTTCACCTGCACGGCGTCCCGACGCAGATGTGCCGTGAGAAGGAGGAGCTGGTCGAGCTGGTTCTCGGCCAGCAGACGCCCACGTCTGACACGCACATTCCAGCCCCAGAAACCACACGCTTAGACCAGCAGGAGACCCTGGACACTCCCGTCATTACAGTGAGCCCGTCAGGGAACAACAACACAACAGAACTGGGACCACAAACACAAGCCATGGACAATGGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000042833_MULTIEX1-2/4=1-3
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
In the CDS, with uncertain impact
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.034 C2=0.449
Domain overlap (PFAM):
C1:
NA
A:
PF0231811=FYVE_2=PU(37.1=44.1)
C2:
PF0231811=FYVE_2=PD(60.0=32.8),PF102084=Armet=WD(100=57.0),PF0203722=SAP=WD(100=16.4)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACGTCACAGTTTACAAGACACTGA
R:
CTCGACCAGCTCCTCCTTCTC
Band lengths:
249-438
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]