DreEX6051439 @ danRer10
Exon Skipping
Gene
ENSDARG00000076270 | adamts13
Description
ADAM metallopeptidase with thrombospondin type 1 motif, 13 [Source:ZFIN;Acc:ZDB-GENE-070814-7]
Coordinates
chr8:45243898-45249390:-
Coord C1 exon
chr8:45249209-45249390
Coord A exon
chr8:45248961-45249108
Coord C2 exon
chr8:45243898-45244027
Length
148 bp
Sequences
Splice sites
3' ss Seq
TTCTAAAATTATCTTTTTAGGTG
3' ss Score
9.44
5' ss Seq
GAGGTAATA
5' ss Score
7.96
Exon sequences
Seq C1 exon
CTGTGTTATTAAATGATAAATATGTTGTTTCTGGAAATGGAAAGCCAGGGCTAAGCAATACATACCCCTCACCTCTGGAGAAGAGCCTTATAACGTATAAACTATACCTCACACCTGACCACCTACCTCAAACTGAAGAGCTCTATATTTCTGGACCAGTCACAGACAAAATCCACTTACAG
Seq A exon
GTGTATCGGAAATATGGACAAGAGTATGGAGACCTCACCAATCCAAATATCTCATACCAGTACTACTCAGATGATGTTATAGTGGAAATAGCTTCAAAGGGCAAATGGTCCACTACCATATCTGCCTGCTCAGTGACCTGTGGAAGAG
Seq C2 exon
GCATCCAGAAAATTTATCAACACTGTGTGGATCTGGTCACACTTGAACACCTGAAAGATGAGCTCTGCAGTTCACTACCTCGGTCGTCTGACCTGCTGCAGCCCTGCTTCCTGCCAGATTGCCCACCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000076270-'16-19,'16-18,17-19=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF059869=ADAM_spacer1=FE(49.2=100)
A:
PF059869=ADAM_spacer1=PD(19.4=48.0),PF0009014=TSP_1=PU(26.3=30.0)
C2:
PF0009014=TSP_1=PD(71.9=93.2)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACATACCCCTCACCTCTGGAG
R:
GTGGGCAATCTGGCAGGAAG
Band lengths:
249-397
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]