DreEX6083919 @ danRer10
Exon Skipping
Gene
ENSDARG00000057918 | tsc1b
Description
tuberous sclerosis 1b [Source:ZFIN;Acc:ZDB-GENE-030131-3404]
Coordinates
chr21:17282931-17286096:+
Coord C1 exon
chr21:17282931-17283049
Coord A exon
chr21:17285693-17285858
Coord C2 exon
chr21:17285978-17286096
Length
166 bp
Sequences
Splice sites
3' ss Seq
GTGCTTGTGTTTATTTTTAGAAC
3' ss Score
9.44
5' ss Seq
CTGGTGACT
5' ss Score
3.06
Exon sequences
Seq C1 exon
GAAGTTCTTCTTCGACTCATTTCTCCACCCCTCGTCAGCCTGTCGTCCCTCCCTTGGCCTTGTCCTCTATCTCAGGGACTCAGCCCCCCTACCGCAGCCCCACTGGAACCCGTCGGCAG
Seq A exon
AACTCCAGCTGTGAATTTAATGCCACATATGGGGTTAAGGATTCTCTCTGGAGCCCCTCCTCCCAGTGTGGGATGGCCACTCCCCCTTCCTCCCGTGGGATGTCACCAAACCCGGAACTGTCCCAGAGTGCCTCTCACCTACCGAGCCGCCTCTACAGCACACCTG
Seq C2 exon
CAGGTGGAAAAGGCACCCCGTCCTCCAGCACGCCTGCAGCTGCAACACCTCCTCCTAGTCTATCAGATGAGTATCCCCCTGTATCGACGCCACGCAGCACCGCCAGCCCACCATGCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000057918-'9-11,'9-9,10-11=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=0.786 C2=1.000
Domain overlap (PFAM):
C1:
PF043887=Hamartin=FE(5.2=100)
A:
PF043887=Hamartin=FE(7.3=100)
C2:
PF043887=Hamartin=FE(5.2=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCTTCTTCGACTCATTTCTCCACC
R:
CTTGCATGGTGGGCTGGC
Band lengths:
234-400
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]