DreEX6086388 @ danRer10
Exon Skipping
Gene
ENSDARG00000074914 | DMPK
Description
dystrophia myotonica-protein kinase [Source:HGNC Symbol;Acc:HGNC:2933]
Coordinates
chr10:363999-365149:-
Coord C1 exon
chr10:365081-365149
Coord A exon
chr10:364733-364881
Coord C2 exon
chr10:363999-364092
Length
149 bp
Sequences
Splice sites
3' ss Seq
TCTCCTCCTCTCCTCCTCAGTAC
3' ss Score
9.16
5' ss Seq
CAGGTACAG
5' ss Score
8.68
Exon sequences
Seq C1 exon
GTTCTGCTAAAGGGGGACAGAAGGTGGATCACAGAGTTGCACTACGCCTTCCAGGATGATGATTACCTA
Seq A exon
TACCTGGTCATGCATTATTATGTTGGCGGTGACCTGCTGACGCTGCTGAGTAAGTTTAATGACGGTCTGCCGGAGGAGATGGCGCAGTTTTACCTGGCGGAGATGGTGATGGCCATCGACTCCGTGCACCTGCTGGGATACGTCCACAG
Seq C2 exon
AGATATTAAACCTGACAATATCCTGCTGACGGCAGACGGCCACGCACGGCTCGGGGATTTCGGCTCATGTCTCCGGCTAGAAGATGATGGACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000074914-'3-6,'3-5,4-6=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(9.4=100)
A:
PF0006920=Pkinase=FE(20.9=100)
C2:
PF0006920=Pkinase=FE(13.2=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTCTGCTAAAGGGGGACAGA
R:
AGTCCATCATCTTCTAGCCGGA
Band lengths:
162-311
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]