DreINT0000014 @ danRer10
Intron Retention
Gene
ENSDARG00000008835 | A2ML1 (1 of 13)
Description
alpha-2-macroglobulin-like 1 [Source:HGNC Symbol;Acc:HGNC:23336]
Coordinates
chr3:3654004-3654425:-
Coord C1 exon
chr3:3654249-3654425
Coord A exon
chr3:3654080-3654248
Coord C2 exon
chr3:3654004-3654079
Length
169 bp
Sequences
Splice sites
5' ss Seq
TTGGTATGA
5' ss Score
5.24
3' ss Seq
TGTGTCTTTGATTGGGACAGGAT
3' ss Score
6.32
Exon sequences
Seq C1 exon
GGGACATAATGGGTCGTGCACTGAAGAATCTGGACAATTTGCTACGAATGCCTTCTGGCTGTGGTGAACAGAACATGATCATTCTCGCTCCCAATATTTACATCCTACGATATCTGACAGTAACTGCACAGCTCACCCCAGTCATCCGAGACACTGCAACTGGCTATCTTCAAATTG
Seq A exon
GTATGACTAAATCGTTGTTTACACCAGGGGTACCTTAACCAAGTTCTTTTTCTGCAGAGATTAGCTCCAGCTTACTTGTACGCACCTTTCAGGATGTTTCTAGTATGACTAAGAGCTTGTTTTGGTGGTTCGGGTGTCTAATGGCAGTTTGTGTCTTTGATTGGGACAG
Seq C2 exon
GATATCAAGGAGAGCTGAACTACAGGCACACTGATGGTTCATTCAGCACTTTTGGTTACGATCCATCCAATACATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000008835:ENSDART00000021286:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF105694=Thiol-ester_cl=WD(100=52.5),PF076789=A2M_comp=PU(0.1=0.0)
A:
NA
C2:
PF076789=A2M_comp=FE(10.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGACATAATGGGTCGTGCAC
R:
TGGATCGTAACCAAAAGTGCTGA
Band lengths:
242-411
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]