DreINT0014396 @ danRer10
Intron Retention
Gene
ENSDARG00000074808 | MEGF6 (1 of 2)
Description
multiple EGF-like-domains 6 [Source:HGNC Symbol;Acc:HGNC:3232]
Coordinates
chr11:41143787-41147671:-
Coord C1 exon
chr11:41147549-41147671
Coord A exon
chr11:41143910-41147548
Coord C2 exon
chr11:41143787-41143909
Length
3639 bp
Sequences
Splice sites
5' ss Seq
ATGGTAACA
5' ss Score
4.87
3' ss Seq
TCTAAATGCTGTTGTTTCAGATA
3' ss Score
7.23
Exon sequences
Seq C1 exon
ATATAAACGAGTGTGTCGACGGCAGCTCGTGTTGTGAACATGACTGTACGAACTATCCTGGAGGATACGAGTGTTACTGTACAGCCGGATATCGACTGAACACTGACGGATGCAGCTGTGATG
Seq A exon
GTAACACACATAAACTCACCAGGCCAGATTTTAAGAGAAGCTCATTACTTTTGTTCTTTAGTTGAAATGAAATATATATATATGTTTTGTTGTTTAGAAATATGTTCCAGAGTTTTTCTCTACTGTATATACACTGACAAAAGTGAAACTACACTGTAAAAGCAATATATTGTCTATAAAGGTCATGTGAAGTGCTTTGAAATGTGCATTTTTATTCGATGTTTGACATAATCTCAACCGAAAAATGAAGAGAGGGTGGGACATAGTGTAGCTCCTCCCCTTTTTAAATCAGCTAATAGTGTTTTGTTTTATCACAGCTCTGCCAGCAGGCCCGGATTGGCTAATTGGGAGGACCGGGAGAATACCCGGGGGGCCGCTCCGTTTTTTTGGCCGCGAGGGCCTGTGTCCCTAGCTGCTTGCGCTCTCAGCAGTCGCACTTTAAAAAATGTTTTATTTATTTGACCATAGTCTCACTCTTTTTATTCATTATTTTGCCGCAGCTTCGCGCTTTTAAATTTTTCTTCTCGCAGCCCCGTGAGCAAAATGCAGCCCACAGGTTAATGAAGATGTAACTATTATTCGACCCCAAACGCGGCACCTTAGTGAATATAAGAATTCGAATAATTAATGAATATTACACCTGTAGCGGCTTTCCAATGCCGCTAATGTTGGTAGAGTGAGCAAGTTTTTAACGCGTAAAAGTCAGAGTCCGTAGGCAAATAGATGCAAATAAAAACGTCTTTATTTACCAATCAACTTCCAATCAACAGAACTACTCAATCACTTCCTTAATCTATATGCACACTTGTCTGTTACCTTGAGTTACGCTTAGTTACAAGACGAGACGTTCAGTTACAAGTCAAGACGATACGGTCAAAAACTGTGGGCTTCCTACCAACACTGTCTTACTCCATGCAGTGAAGCCACACTTACCTGTATATAGTCTCCTACTGACACCTTGTGGCCAATAGCCAAAATACAATGTATGCTCCTACAACACCTGCTCAATGAAAATCAGATGATTCACTACATTAATAAATCTGACATAAATTGATCAGAAATCTAGAAAGGGGAGAAAAAGATTAAGTCGTCAATAGACAAGTTTTTAACAACAGCGCCATTGTGGTCCAGTGGTCAGCACGTTGTGTTACCACACTGCAGGACCCGAGTTTGATCCTTACCTATCTGATTGAATTTATTTATTTATTTAATTTCATTTTTATTGTGAAGACATATAATACTGTTTGGGTTGTTGAACATTTCAACTTATAAAGCAGCTGTTTTCTTGAAAAATACGTGATCGTGTCATTAGAAACTGAATTCAAAATGACGTTATTTTAATATAGTCAGTCGTGAACTGAGGTGGACCGGTCTAAGGCTTGAAACTCCAGGGGCCTCATGTATCAACGCTGCGTACGCACAAAAACTTTGCGTACGCCAGGTTTCACGCTCAGAATCGCTCACGTTTGGATTTACTAACAATGAACTGAACGTGGGAATGTGCGCACCTTCACGGCAGCTTTATGGCTGGCGTACGCATATTTTTTGTGCGTGTCTGTTTTATTTCCATTGGCGACTCCTAGAGGCAGTTGTGTTAAATTCCTCTCTACAAAGTGTCTGAGCCTTGCAATGGCAGCTGTATGAGACGGGTTCAGCAGGTATATAAGGTTTCCATACCATACAGTTGACCAGCTAAACATTAAAGCACAATTTGCAGCGGTCGCCTGTTTTCCCAATGTAATCTGAGCGATCTACTGCACGAACATTGCTATAAAGACACTATCTAAAGATGAATTTGCATGCGTGAATCAGAAACATTTCCATTCTATAAATGTGCAAATAAAATATGATGCACAAACTTATCGATTCCTACTTGTCTTTCTCGTGATAAATAGTTGGCAAAATCTGATATGTAGCGGGGGAAAAAAGAAGAAAGAGTTCATCAGATGCTAGATTCGAACCGAGTTCATGCTCGAACGTGTCAAAACATGTTGACATGCGCTTTATGAGCTGCGCCACTGAGACTGTTACGAGTATTGCAACATTTTACTCCTATAAACCACACTAGTTTTTTCTTTTGTTGTTAATTCCGGAGAACAAACTTGCAAATAACACCGCTTTTCTCCGGTCTACCTCCAAAAGCAGCACCTCCAATTCACATTCTGTTCAAAGTTTCTCTTTTTGCGTGATTTTGTCATTGCTTTTTCGTTGAGTTTTGCCATTAGCATAGTCATTAGCATATTCATACGGGGGAGGAGCCAGGGAAGGGTTTTGTGCATGTGCATGTTACGCTTAGTTTCACGTTCATTCAGATGTACAAAAGAATATGCGTGAGATTCGGCGTACGCAGTGTTTCATACATCTGAATTTTTTTCTGCGTACGCACTTTTACAGCTTTGTGTGTACGCAATGTTTTAGTATGATTTCCATGCAAGTCTTCGTACATGAGGCCCCAGGGCTGAAAAGGAGTCCCACTGCGGCCCTGTCTGCCAGTGAGACCAGTTGAGCTCAAGCGCATCAAATGAGAAGCTTCTTGAAGGTGGCAGTGCATGTCAGATACTAGAGAGCATTTGATTGGTTACGATTTGATGAGAAACTTAAGTATGAGGTGACGTAAAACAAAACGTTGATACATATAGGCGCAAGTGACAAACACCAAGCCTTACATGTTTATATCAGTTTTTTTTTATTGTGTTTTTGACAAAAGGTACAGTACATTAAAGGTATTCAATTACAAAGGTATTTTCGTTTTTTCTTTTTTTGAACCATACATAAATTGAAAAAAAAAAAAGACAAATTAACATAATAAAAAAAAATTATGAAACGGAAATGCATTAAATAAAAAATATATTAATAATAATAAAAATGAAAATAAAATAAATTTACAGAAAATAAATAAATAAATAAATAATAAAAAAATAATAATAAATAAAAATTTAATTAATAAAAAATAAAAATAAAAAAGGTGGGTGGGGGTGGGGTTGGGAATTTATGGTTGGAGGAGTACATTAGTCTCAATATGAATTATTAGAGGGTCCCATGTTTTGAAAAATGTTTTGGTTGATCCTCTGAGAAAATATAAAATTTTTTCTGTTTTCAAAAATAGCATTACATCACTAAGCCAAAGTGACAGTTTAGGTGGCATTGGTGATTTCCACTCCATAAGAATTCTTCTTCTAGCTATTAATGTTACAAAGGCAAAGGCGTTTTCTATTTCTTTAGCTACATGGATGTCCTCATTTGTTACTCCAAAAATAGCCATTTCCGGATTTGGTTGAATTCTTAAATTGAAGGCTGAGTTTAAAATTTCAAATATTGAAGACCAAAATCGTCTCAGTTTGTCACATGACCAGAACATATGGGTTAGGTCTGCCTTGCACAAGTTGCAACGATCGCATGTTTCATCTATATTGGGGTAGATTAGTTTTATATCTTCTAATTGTGAATTTTGTCACTGCTTTGGAGCACACAAATATCTTAAAAGCTAACAATACTGATACTAACATCTAAAAAACTTTTAATTTCATGGCATCTTTAAAATGATAAGTTAAGTGAACTTAACTGTTCTAAGTTAAAACAGAATTGCGTACGTTTTGATCTGATCTGATTAATTGTATTGTCTAAATGCTGTTGTTTCAG
Seq C2 exon
ATATAGATGAGTGTTTGGCTGTTAATGGAGGATGTGATCATGCTTGTCTGAACAGCGCCGGCTCTTTCCAGTGTTCCTGTAGACGTGGATATCGACTCGATGAGGACAGAAGATCCTGCATAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000074808:ENSDART00000109204:11
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF126622=cEGF=PD(13.6=7.1),PF126622=cEGF=PU(83.3=47.6)
A:
NA
C2:
PF126622=cEGF=PD(12.5=7.1),PF146701=FXa_inhibition=WD(100=85.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]