HsaINT0101814 @ hg38
Intron Retention
Gene
ENSG00000162591 | MEGF6
Description
multiple EGF like domains 6 [Source:HGNC Symbol;Acc:HGNC:3232]
Coordinates
chr1:3509870-3510902:-
Coord C1 exon
chr1:3510783-3510902
Coord A exon
chr1:3509993-3510782
Coord C2 exon
chr1:3509870-3509992
Length
790 bp
Sequences
Splice sites
5' ss Seq
AGGGTGAGC
5' ss Score
7.75
3' ss Seq
TGGTCCCGGGTCGCCCGCAGATG
3' ss Score
8.4
Exon sequences
Seq C1 exon
ATGTCGACGACTGTGCAGACAGCCCGTGCTGCCAGCAGGTGTGCACCAACAACCCTGGCGGGTACGAGTGCGGCTGCTACGCCGGCTACCGGCTCAGTGCCGATGGCTGCGGCTGTGAGG
Seq A exon
GTGAGCACTGCCCTGCCACTGCACAGCTGGGGTGGCCTGGGAGCAGGGCTGCCCTAAGGAAGGACACGGGGCTGGCTCTGGTACCCCCATGGTGGGCATGGGGTCGGCCTGCTCTGTGCTTTGCTTTGGGGCTGTGGGTGTTGGTTGAGCGCCTGCTGTGTGCAGGGCTGTGGTGGGTGTTGGTTGAGCGCCTGCTGCGTGCAGGGCTGTGGGTGTTGGTTGAGCCCCTGCTGAGTTCAGGGCTGTGGGCGTTGGTTGAGCACCTGCTGCGTGCAGGGCTGTGGGCGTTGGTTGAGCGCCTGCTGCGTGCAGGGCTGTGGGTGTTGGTTGAGCGCCTGCTGCGTGCAGGGCTATGGGTGTTGGTTGAGCCCCTGCTGAGTTCAGGGCTGTGGGCGTTGGTTGAGCGCCTGCTGCGTGCAGGGCTGTGGGTGTTGGTTGAGTGCCTGCTGCCTGGAGGGCTGTGCTGACCTGTCCCCTCCCTCCCTCTGGCCTGAGGTCACTGGCCGCTCTCTCCTGGAGCTGGGCCTGTCCCCCTGGCTGCTGCCTGGCCGGCCCCTCCCAGCCTGGCCCCCCCTAGCACGTGTCTGCCATGGCTCTGACCCTGGGCTGGGAGGATGGCCAGAGTGGCCTCTGTGGCTGAGGGTGAGTTTTACTGGCTGGTTGAAGAGATGCTACTCAGCTCTGGCAGGGCCACCAGGGCTTCAGTCCTGTGGGTAGGACTGGGTGGGCAGGGGCCTTCCTGGTTCCCCACCTGGGAGCACAGGCCTCAGTGGTCCCGGGTCGCCCGCAG
Seq C2 exon
ATGTGGATGAGTGCGCCTCCAGCCGTGGCGGCTGCGAGCACCACTGCACCAACCTGGCCGGCTCCTTCCAGTGCTCCTGCGAGGCCGGCTACCGGCTGCACGAGGACCGTAGGGGCTGCAGCC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162591:ENST00000294599:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF146701=FXa_inhibition=WD(100=85.4)
A:
NA
C2:
PF146701=FXa_inhibition=WD(100=85.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGTCGACGACTGTGCAGACA
R:
CAGCCCCTACGGTCCTCG
Band lengths:
238-1028
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development