DreINT0024625 @ danRer10
Intron Retention
Gene
ENSDARG00000013841 | abl2
Description
c-abl oncogene 2, non-receptor tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-020809-2]
Coordinates
chr8:14930285-14932801:+
Coord C1 exon
chr8:14930285-14930580
Coord A exon
chr8:14930581-14932528
Coord C2 exon
chr8:14932529-14932801
Length
1948 bp
Sequences
Splice sites
5' ss Seq
AAGGTATAA
5' ss Score
7.08
3' ss Seq
AAAAAGCTTTTCTGTTTCAGGTC
3' ss Score
8.9
Exon sequences
Seq C1 exon
GAGAGAAGCTGCGAGTGTTGGGTTATAACCAGAATGGAGAATGGAGTGAAGTCCGCTCAAAGAACGGCCAGGGCTGGGTACCCAGTAACTACATCACCCCCGTAAACAGTCTGGAGAAGCACAGCTGGTACCATGGGCCCGTGTCCCGCAGCGCTGCCGAGTACCTGCTCAGTAGCTTGATCAACGGCAGCTTCCTGGTGCGGGAAAGCGAGAGCAGCCCCGGCCAGCTCTCCATCTCTCTTCGCTATGAGGGACGGGTCTATCATTACCGCATCAACACGGCCTCTGATGGAAAG
Seq A exon
GTATAAGAGCTTTACTTTGCCATCGTGCTTCTTTTGCCTAAAAGGGAGGGATGGTTCACCCCAAAATTTTTTATTCTGTAATTTTTTTTTCTCCCTTCACTTGTGCCAAACCTGGTTACATTTCTTTTTATTTATTTTTTTACACTGGCACAAAAATTCTTACACTGGTGCAAAAAAACAGATGCACTGCATAGAAAAGGACTTGATCATCCCAGTCCCTCTCACTGAATAAAATCTTTCTAAATAGAGCTATTCAAATCATCTGGTGAAATTATGTTCATCTCGCTATATATAATGCAGCCAAAACATATTGCAATGTCAGATTTTTCCAATATTGTGCAGCACTAGTATACATTATTTTTTTACAACCGCTTTTAAAATCTTATACTGTATATGAGATAAAGGGGGGACAAAGGGATCAAAGGGAAAAATGGAGAAACAAACTAAAGAAAAAATAATCTGGGCTGTTTCTGTTAGGCTTCAATTTCTGTGTTCTTGTTAAAGTATTCAATAAATGGCTTCCATAAAAGTTCTTAGCTTTTTTTTTAGGGAAAGTCTGATATTTTCAAGATATATCATAACATTTTGTTCCAAACCTGTTTGACTTTTTTGGTTGAATTTTAAAGCAGAAATTTTGAAGAAAGTAAGAAACCTGTAACCGTTGAATTCCATAGTGAGGCGACCCCTTGTGGTCATTTTTCATTGGGGTATGGGCATCTGTTTGTGTGCGGCTGCGTGTGTTTGTGCGTTACAGGTTTAGCTTATTGCGCCGGGATTGAAAACACCGGTGTATGGTTGATCTTCCCTGCTAAAAGTAGAGATATGATTCTCTCTGGGATGCGCGAGGTCCCGAACAGATCTTGGACAAGCCCATAATTGTTAAGACCTAAACCAGTCACCACAAATAAGAAGATGAGCGCATTTGCGGTACAAAATTTTTTTTTCTTTTTTCATTAATCATATTTTTAGCTCTACTCAGGTCCAAGACCGACTCAAGACGGAAGATAGGCGATGACTAGACTCTGACTGCAGCCTTCACTATGTCTGAGACAGACACGCTACTTATAGCAGGGCAAATCAACCTTACACAGGTGTTTTTAATCCCAGCGCAATCAGCCGAACCTGTAACACAGACACACGCAGACGCACACAAACAGACACCCCAACAAAAAAATGACCACAAGGATTCCCTATTTGTAGGGAATGCACCAATCCCAATACTTAGATAGGATATCGGTTCGATAACGCATATTTTTGCTGGATTGGGTATCGGCCAGCGCTTCATCCTTCATCCATCAAACTGAGTTTATATTCTTCCGAGGGGGATACTTTCAGAGCTGTAAATAGTTTGTAAAGCCTGGCTCATTGTTGTCAAAGTAATTGATTAAATTAATAAAAGGAAAGTGATGGGTGCAATATGGATTGTCATTAACAGTAAAAGGAATATTTATTAAGTAAAACTGGCCTCATACAGTTTAGTTTAGTCTGCGTCAAACCTGCAGGAAAATATCAGGCTTTGCTAAAAAGTCTGGTTATTTTACCAACGATTAGGGTCAATACTGGTAGCCCATTACAGATTTCAAAGAAAATGTCATAACAAATGCTCAAATAATGTAGCCTAGTGAAACGCAAACATCATGTTTTTAGTTTGACTGTGTGTCTGTCATATACAGTAGGCCTTTGGTTCTGTTATTTTTATCAAAGAAGATATTATTTGACCAGAATTATTTCACCAAAATTATAAAAACTGTCTTATGCTTTAAAAAAAAAAAAGATCGAGATCTGATTGGTTCCAAAAAAAATAGTTTATATTTTAGTTCATATTTGTTTTTCTTACTATGTAAGTTTATGGTTCCATGTTTGGAACCTCTTGAGAAATAATAAATGGTGAGTAAATGTAATTTTGGGGGAAACTGTCCCTTTAAATTAAAAAGCTTTTCTGTTTCAG
Seq C2 exon
GTCTATGTGACAGCAGAGAGTCGTTTCAGCACGTTAGCTGAGCTGGTTCATCATCATTCCACAGTTGCGGATGGACTGGTAACCACTCTGCATTATCCTGCTCCCAAATGCAACAAGCCCACCGTCTACGGCGTCTCTCCCATCCACGACAAGTGGGAGATGGAGCGCACCGACATCACCATGAAGCACAAATTGGGTGGAGGACAGTACGGAGAGGTGTACGTTGGAGTTTGGAAAAAGTACAACCTCACTGTAGCTGTAAAAACACTAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000013841:ENSDART00000041697:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.010 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0001823=SH3_1=PD(59.6=28.3),PF0001719=SH2=PU(73.7=56.6)
A:
NA
C2:
PF0001719=SH2=PD(23.7=19.8),PF0771412=Pkinase_Tyr=PU(12.7=35.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTAGCTTGATCAACGGCAGCT
R:
CCTCTCCGTACTGTCCTCCAC
Band lengths:
342-2290
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]