GgaEX0028718 @ galGal4
Exon Skipping
Gene
ENSGALG00000003135 | chAnk3
Description
ankyrin 3, node of Ranvier (ankyrin G) [Source:RefSeq peptide;Acc:NP_001264026]
Coordinates
chr6:8502378-8516386:+
Coord C1 exon
chr6:8502378-8502756
Coord A exon
chr6:8506016-8506114
Coord C2 exon
chr6:8516294-8516386
Length
99 bp
Sequences
Splice sites
3' ss Seq
ACTAAAACTGCATTTATTAGGAA
3' ss Score
3.08
5' ss Seq
AAGGTATTT
5' ss Score
7.64
Exon sequences
Seq C1 exon
CTCGGACCAATGTAGGGACTCTGTTACCTCATATGTCAAAGGAGAAGCAGGGAAGCCAGAAACAAATGGAAGCCTCTCAGAAACCACAACAGAAACAAAAACTAAATCCTATGTCCAGGAATCTTTAAATGACGTGGGAAAACACAGTGACAAAGAAGCCCTGAAAACAAAGTCCCAGATTTCAGCTGGTACTGATGAGCAAACGTTATCATCAACAGCATATCAGAAATCTTTGGAAGAGACTAGCAAGCCAACAACAGAAGGCAACAAAACATCTGTGCCCGTCAGTGTGAAGAAGATGGGCTGGAGTACTTCAGAGGATGGCAAGGCAAGAGCAGGCATCCAAGAGGAGGAGGGAGCAGGAATGTCTGAGCAGAAG
Seq A exon
GAATGTAGTGACAGTGACAGTGAGATTGAGAGTGATTCGAGCTCAGGTGAGGAGCAGAGGATTACTACAAGAGTGTATCGACGGCGGTTGATTCTGAAG
Seq C2 exon
CAGGGCGAAGCTTACAAGGTTAAGACAAAGAAAGAAGTCAGACACGTGGAGAAGAAAAGTTACTCGTGAAAGCTGAAAGCCAACCACTGACCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSGALG00000003135_MULTIEX1-1/3=C1-C2
Average complexity
ME(1-3[100=100])
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=0.909 C2=0.864
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGGCTGGAGTACTTCAGAGG
R:
GTCAGTGGTTGGCTTTCAGCT
Band lengths:
171-270
Functional annotations
There are 1 annotated functions for this event
PMID: 21223964
Ankyrins-G coimmunoprecipitated with plectin and filamin C from skeletal muscle tissue extracts. Muscle-specific OTBD domain (coordinated inclusion of MmuEX1003810, MmuEX1003809, MmuEX0004908) is required for ankyrin-G binding to plectin and filamin C. Isoforms are differentially expressed during myogenesis.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]