GgaEX1066076 @ galGal3
Exon Skipping
Gene
ENSGALG00000003578 | FN1
Description
NA
Coordinates
chr7:4366567-4368633:-
Coord C1 exon
chr7:4368544-4368633
Coord A exon
chr7:4367250-4367716
Coord C2 exon
chr7:4366567-4366705
Length
467 bp
Sequences
Splice sites
3' ss Seq
TCTAACCTTTCTTTGGCTAGATG
3' ss Score
7.6
5' ss Seq
CAGGTAACT
5' ss Score
8.63
Exon sequences
Seq C1 exon
GCTTAGAACCAGGGACCGAATACACAATCTACATCATTGCTGTGAAGAACAATCAAAAGAGTGAACCACTGGTTGGCCGAAAAAGGACAG
Seq A exon
ATGATCTGCCCACGTTGATTACTGGACCGCACCCCAACCAGCCCGACATGCTCGACGTACCTTCTGTTGATGAGGGAACCCCTTACCTCACAAACAATAGGTATGACAATGGAAACGGTATCCAACTTCCAGGCACTTCAGGGCACCCACAGACAATAGGACACCAAGGTCAGCAAGTCTTCTTCGAGGAGCATGGCTACAGGAGGCCTGTACCCACGACAGCAACTCCCCTTAGGCCTGGGTCGAGACGGCAGCCACCAAATGTAGATGAAGCAATTGAAATCCCAGGGTACCAAGTGCCAATCATAGTTGTACCTTCATACCCCCACTCCCGTGAGCCCAGACGCAACGACACCACGGGCCAAGAAGCTCTTTCTCAGACAACCATCTCCTGGAGGCCTTTGCTGGAGAGCACTGAGTACATCATCTCATGCCAACCAGTCAGCCAGGATGAAGATACTTTGCAG
Seq C2 exon
TTCAGGGTTCCTGGCACTTCCTCCAGTGCTACGCTCACTGGCCTCACCAGAGGTGCCACCTACAACATCATAGTAGAAGCCCTGAAGGATCACCGCAGACAAAAGGTGCTGGAGGAGGTGGTCACAGTTGGCAATACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSGALG00000003578-'40-45,'40-43,41-45=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.419 A=0.795 C2=0.128
Domain overlap (PFAM):
C1:
PF0004116=fn3=PD(27.2=71.0)
A:
PF0004116=fn3=PU(53.8=26.9)
C2:
PF0004116=fn3=PD(43.6=72.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTTAGAACCAGGGACCGAAT
R:
ATTGCCAACTGTGACCACCTC
Band lengths:
225-692
Functional annotations
There are 1 annotated functions for this event
PMID: 11246004
The alternatively spliced IIICS segment possesses the major alpha4beta1 integrin-binding sites. The exon is associated to HsaALTA0003426 and other complex AS events.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]