GgaEX1066076 @ galGal4
Exon Skipping
Gene
ENSGALG00000003578 | fn1
Description
fibronectin precursor [Source:RefSeq peptide;Acc:NP_001185641]
Coordinates
chr7:4338845-4340228:-
Coord C1 exon
chr7:4340139-4340228
Coord A exon
chr7:4339212-4339311
Coord C2 exon
chr7:4338845-4339179
Length
100 bp
Sequences
Splice sites
3' ss Seq
TCTAACCTTTCTTTGGCTAGATG
3' ss Score
7.6
5' ss Seq
TAGGTATGA
5' ss Score
6.99
Exon sequences
Seq C1 exon
GCTTAGAACCAGGGACCGAATACACAATCTACATCATTGCTGTGAAGAACAATCAAAAGAGTGAACCACTGGTTGGCCGAAAAAGGACAG
Seq A exon
ATGATCTGCCCACGTTGATTACTGGACCGCACCCCAACCAGCCCGACATGCTCGACGTACCTTCTGTTGATGAGGGAACCCCTTACCTCACAAACAATAG
Seq C2 exon
GCACTTCAGGGCACCCACAGACAATAGGACACCAAGGTCAGCAAGTCTTCTTCGAGGAGCATGGCTACAGGAGGCCTGTACCCACGACAGCAACTCCCCTTAGGCCTGGGTCGAGACGGCAGCCACCAAATGTAGATGAAGCAATTGAAATCCCAGGGTACCAAGTGCCAATCATAGTTGTACCTTCATACCCCCACTCCCGTGAGCCCAGACGCAACGACACCACGGGCCAAGAAGCTCTTTCTCAGACAACCATCTCCTGGAGGCCTTTGCTGGAGAGCACTGAGTACATCATCTCATGCCAACCAGTCAGCCAGGATGAAGATACTTTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSGALG00000003578_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.435 A=0.876 C2=0.722
Domain overlap (PFAM):
C1:
PF0004116=fn3=PD(27.2=71.0)
A:
NO
C2:
PF0004116=fn3=PU(54.5=53.8)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAACCAGGGACCGAATACACA
R:
GATTGGCACTTGGTACCCTGG
Band lengths:
258-358
Functional annotations
There are 1 annotated functions for this event
PMID: 11246004
The alternatively spliced IIICS segment possesses the major alpha4beta1 integrin-binding sites. The exon is associated to HsaALTA0003426 and other complex AS events.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]