HsaALTA1009253-2/2 @ hg38
Alternative 3'ss
Gene
ENSG00000092871 | RFFL
Description
ring finger and FYVE like domain containing E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:24821]
Coordinates
chr17:35021622-35026561:-
Coord C1 exon
chr17:35026374-35026561
Coord A exon
chr17:35021782-35021784
Coord C2 exon
chr17:35021622-35021781
Length
3 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGT
5' ss Score
10.47
3' ss Seq
CCTGTGTCTTTTGCTCTAAGCAG
3' ss Score
4.72
Exon sequences
Seq C1 exon
ATTTTATCATGTGGGCAACCTGCTGCAACTGGTTCTGCCTGGATGGACAGCCTGAGGAGGTCCCACCACCCCAGGGAGCCAGGATGCAGGCCTATTCCAACCCTGGGTACAGCTCCTTCCCTTCCCCAACAGGCTTGGAACCAAGCTGCAAGTCCTGTGGGGCTCACTTTGCAAACACGGCCAGGAAG
Seq A exon
CAG
Seq C2 exon
CAGACCTGCTTGGACTGTAAGAAAAATTTTTGCATGACCTGTTCGAGCCAAGTAGGGAATGGGCCCCGCCTCTGCCTTCTCTGCCAACGGTTTCGAGCTACAGCCTTTCAGCGAGAGGAGCTCATGAAGATGAAGGTGAAGGACTTGAGGGACTATCTCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000092871-6-20,6-19-2/2
Average complexity
Alt3
Mappability confidence:
NA
Protein Impact
Protein isoform when splice site is used (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.110 A=NA C2=0.371
Domain overlap (PFAM):
C1:
PF0231811=FYVE_2=PU(27.7=30.0)
A:
NA
C2:
PF0231811=FYVE_2=PD(68.2=48.9),PF102084=Armet=WD(100=67.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAACCAAGCTGCAAGTCCTGT
R:
ACTTGGCTCGAACAGGTCATG
Band lengths:
104-107
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains