HsaALTA1039804-2/3 @ hg38
Alternative 3'ss
Gene
ENSG00000162591 | MEGF6
Description
multiple EGF like domains 6 [Source:HGNC Symbol;Acc:HGNC:3232]
Coordinates
chr1:3497233-3498499:-
Coord C1 exon
chr1:3498371-3498499
Coord A exon
chr1:3497362-3497411
Coord C2 exon
chr1:3497233-3497361
Length
50 bp
Sequences
Splice sites
5' ss Seq
GCCGTGAGT
5' ss Score
8.56
3' ss Seq
CGGCCTGTCCTGGCCCACAGATC
3' ss Score
10.63
Exon sequences
Seq C1 exon
AGTGCCTCCCCCGGGACGTCAGAGCTGGCTGCCGGCACAGCGGCGGTTGCCTCAACGGGGGCCTGTGTGACCCGCACACGGGCCGCTGCCTCTGCCCAGCCGGCTGGACTGGGGACAAGTGTCAGAGCC
Seq A exon
ATCCCCACGGGCCCCTCCTAGAAGCCTCCGCAGCCCTCATCTTTCTGCAG
Seq C2 exon
CCTGCCTGCGGGGCTGGTTTGGAGAGGCCTGTGCCCAGCGCTGCAGCTGCCCGCCTGGCGCTGCCTGCCACCACGTCACTGGGGCCTGCCGCTGTCCCCCTGGCTTCACTGGCTCCGGCTGCGAGCAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162591-62-64,62-63,62-62-2/3
Average complexity
Alt3
Mappability confidence:
NA
Protein Impact
ORF disruption when splice site is used (sequence inclusion)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.051
Domain overlap (PFAM):
C1:
PF079748=EGF_2=WD(100=70.5)
A:
NA
C2:
PF0005319=Laminin_EGF=PU(67.4=65.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGACTGGGGACAAGTGTCAGA
R:
AGTGAAGCCAGGGGGACAG
Band lengths:
134-184
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains