HsaINT0101831 @ hg38
Intron Retention
Gene
ENSG00000162591 | MEGF6
Description
multiple EGF like domains 6 [Source:HGNC Symbol;Acc:HGNC:3232]
Coordinates
chr1:3497233-3498499:-
Coord C1 exon
chr1:3498371-3498499
Coord A exon
chr1:3497362-3498370
Coord C2 exon
chr1:3497233-3497361
Length
1009 bp
Sequences
Splice sites
5' ss Seq
GCCGTGAGT
5' ss Score
8.56
3' ss Seq
CAGCCCTCATCTTTCTGCAGCCT
3' ss Score
6.58
Exon sequences
Seq C1 exon
AGTGCCTCCCCCGGGACGTCAGAGCTGGCTGCCGGCACAGCGGCGGTTGCCTCAACGGGGGCCTGTGTGACCCGCACACGGGCCGCTGCCTCTGCCCAGCCGGCTGGACTGGGGACAAGTGTCAGAGCC
Seq A exon
GTGAGTGGGGCGGGGCAGCAGGGGGGTCTGCAGGCCCTGCTGGGAAGGGGTGGCATCAGCCTTACTGCAGGGCTGAGGACTGTGCCCGGTTTGGGGCCTCACCAGGGGACCTGTTGTCCTGTGAATGCAAGAGCTGCCGTCGGAGCACTAAGACCCTGTTGGGAGGGTCTCAGCCTAGGAAGCTGGCCTGTGGGGACAGAGTGCTGCTGCTTTGCCTTGGCAGGGGTAGCCCCAGCCAGCCCTGTGGTGGGTGGAACGGAGGATGCTTTGGGGCTCAGGGGGCCGTTCCTGTTTCCTGCATGCAGAGAGGGGCCCCTTCACCCCTTGTCCTGGAGCCTGTGCTGGCTGGGGGCCTCCTGCCAGTGGGAGTCTGGCTGTGGCTGCTGTGCCGGCAGGGCCTGGTCCACCCAGCGGGGCCTCAGCCCCTCCAGAGCCCAGACATGCAAGGGCAACACTGCCTCATTCCTCAAAGCCCCGGCCTCCCACCCAAGCCCCTAACACGAGCCCCCCTTCCAGCAGAGGCGCCGTCCCCACTGCTTGGGGTACAACTTGGGCGGTCCCTTGCTCAGGTCAGGAGCCTTGGGTCTGCTGTCTGAGGGGGGCCTGGGCACTCGGCTGGCCTCAGGGCTGTCGCTGGCTCCCGTCGCCTCAGTGCTGAGCCCCGGCTGCTGTCTCCCGGCTCCTTCGCCTTCCATGGGGCGGGGCTGCCAGAGGCTGAGCTCTCAGCCCTATCTGTCTCGTCCCTGCAGCCTGTGCCAAGGGCACATTCGGGCCTCACTGTGAGGGGCGCTGTGCCTGCCGGTGGGGAGGCCCCTGCCACCTTGCCACCGGGGCCTGCCTCTGCCCTCCGGGGTGGCGGGGGGCTCCAGGTGTGAGAATGGTGAGCACAGCCCCCAGTTCAGCCAGCATTGGGTGGGTCGTACCCACAGCACCTGCTCCCGGCCTGTCCTGGCCCACAGATCCCCACGGGCCCCTCCTAGAAGCCTCCGCAGCCCTCATCTTTCTGCAG
Seq C2 exon
CCTGCCTGCGGGGCTGGTTTGGAGAGGCCTGTGCCCAGCGCTGCAGCTGCCCGCCTGGCGCTGCCTGCCACCACGTCACTGGGGCCTGCCGCTGTCCCCCTGGCTTCACTGGCTCCGGCTGCGAGCAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162591:ENST00000294599:21
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.051
Domain overlap (PFAM):
C1:
PF079748=EGF_2=WD(100=70.5)
A:
NA
C2:
PF0005319=Laminin_EGF=PU(67.4=65.9)
Main Inclusion Isoform:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGACGTCAGAGCTGGCT
R:
CAGCCGGAGCCAGTGAAG
Band lengths:
238-1247
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development