HsaALTA1039804-3/3 @ hg38
Alternative 3'ss
Gene
ENSG00000162591 | MEGF6
Description
multiple EGF like domains 6 [Source:HGNC Symbol;Acc:HGNC:3232]
Coordinates
chr1:3497233-3498499:-
Coord C1 exon
chr1:3498371-3498499
Coord A exon
chr1:3497362-3497441
Coord C2 exon
chr1:3497233-3497361
Length
80 bp
Sequences
Splice sites
5' ss Seq
GCCGTGAGT
5' ss Score
8.56
3' ss Seq
TGGGTGGGTCGTACCCACAGCAC
3' ss Score
5.98
Exon sequences
Seq C1 exon
AGTGCCTCCCCCGGGACGTCAGAGCTGGCTGCCGGCACAGCGGCGGTTGCCTCAACGGGGGCCTGTGTGACCCGCACACGGGCCGCTGCCTCTGCCCAGCCGGCTGGACTGGGGACAAGTGTCAGAGCC
Seq A exon
CACCTGCTCCCGGCCTGTCCTGGCCCACAGATCCCCACGGGCCCCTCCTAGAAGCCTCCGCAGCCCTCATCTTTCTGCAG
Seq C2 exon
CCTGCCTGCGGGGCTGGTTTGGAGAGGCCTGTGCCCAGCGCTGCAGCTGCCCGCCTGGCGCTGCCTGCCACCACGTCACTGGGGCCTGCCGCTGTCCCCCTGGCTTCACTGGCTCCGGCTGCGAGCAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162591-62-64,62-63,62-62-3/3
Average complexity
Alt3
Mappability confidence:
NA
Protein Impact
ORF disruption when splice site is used (sequence inclusion)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.051
Domain overlap (PFAM):
C1:
PF079748=EGF_2=WD(100=70.5)
A:
NA
C2:
PF0005319=Laminin_EGF=PU(67.4=65.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCAACGGGGGCCTGTGT
R:
CAGGCCCCAGTGACGTGG
Band lengths:
167-247
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains