HsaEX0003153 @ hg38
Exon Skipping
Gene
ENSG00000188157 | AGRN
Description
agrin [Source:HGNC Symbol;Acc:HGNC:329]
Coordinates
chr1:1041956-1043457:+
Coord C1 exon
chr1:1041956-1042162
Coord A exon
chr1:1042691-1042748
Coord C2 exon
chr1:1043239-1043457
Length
58 bp
Sequences
Splice sites
3' ss Seq
CCGCCTCTTGTGTCTTCCAGCCT
3' ss Score
9.01
5' ss Seq
GAGGTCTGC
5' ss Score
3.9
Exon sequences
Seq C1 exon
ACCAGTGCCCGGAGCCCTGCCGGTTCAATGCCGTGTGCCTGTCCCGCCGTGGCCGTCCCCGCTGCTCCTGCGACCGCGTCACCTGTGACGGGGCCTACAGGCCCGTGTGTGCCCAGGACGGGCGCACGTATGACAGTGATTGCTGGCGGCAGCAGGCTGAGTGCCGGCAGCAGCGTGCCATCCCCAGCAAGCACCAGGGCCCGTGTG
Seq A exon
CCTGACCTGCTGGCAGGATGAGGTGCCGTGCCTGCCCTCCAGGAGCCCGCAGCCCGAG
Seq C2 exon
ACCAGGCCCCGTCCCCATGCCTCGGGGTGCAGTGTGCATTTGGGGCGACGTGTGCTGTGAAGAACGGGCAGGCAGCGTGTGAATGCCTGCAGGCGTGCTCGAGCCTCTACGATCCTGTGTGCGGCAGCGACGGCGTCACATACGGCAGCGCGTGCGAGCTGGAGGCCACGGCCTGTACCCTCGGGCGGGAGATCCAGGTGGCGCGCAAAGGACCCTGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000188157_MULTIEX1-5/5=4-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005016=Kazal_1=WD(100=68.6)
A:
NO
C2:
PF0764810=Kazal_2=WD(100=55.4)
Main Inclusion Isoform:
ENST00000620552fB248
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CATCCCCAGCAAGCACCAG
R:
CACAGGATCGTAGAGGCTCGA
Band lengths:
148-206
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development