HsaEX0003522 @ hg38
Exon Skipping
Gene
ENSG00000198752 | CDC42BPB
Description
CDC42 binding protein kinase beta [Source:HGNC Symbol;Acc:HGNC:1738]
Coordinates
chr14:102940227-102944487:-
Coord C1 exon
chr14:102943891-102944487
Coord A exon
chr14:102940954-102941398
Coord C2 exon
chr14:102940227-102940324
Length
445 bp
Sequences
Splice sites
3' ss Seq
ATTTCCCTTTTTGTATTCAGAAG
3' ss Score
7.73
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
Exon sequences
Seq C1 exon
GCACCTCTATCCGTGGTCGTCCCTTGATGGAGCGGAAGGCAGCTTTGACATCAAGCTTCCGGAAACCAAAGGCTGCCAGCTCATGGCCACGGCCACACTCAAGAGGAACTCTGGCACCTGCCTGTTTGTGGCCGTGAAACGGCTGATCCTTTGCTATGAGATCCAGAGAACGAAGCCATTCCACAGAAAGTTCAATGAGATTGTGGCTCCCGGCAGCGTGCAGTGCCTGGCGGTGCTCAGGGACAGGCTCTGTGTGGGCTACCCTTCTGGGTTCTGCCTGCTGAGCATCCAGGGGGACGGGCAGCCTCTAAACCTGGTAAATCCCAATGACCCCTCGCTTGCGTTCCTCTCACAACAGTCTTTTGATGCCCTTTGTGCTGTGGAGCTCGAAAGCGAGGAGTACCTGCTTTGCTTCAGCCACATGGGACTGTACGTGGACCCGCAAGGCCGGAGGGCACGCGCGCAGGAGCTCATGTGGCCTGCGGCTCCTGTCGCCTGTA
Seq A exon
AAGAAAAGTCCTGATCTTGTAGCCTGTTTGGAGTCTGTGATAGAAACAGAGCAGAAGGCTTTTAAAATGCATCTTCAGACAGTGAGGTGTGTCCTGATGCAGGATTAACCTTGAACTCCGGAGGCAGAAGAGCCAGGAAGGAGCACTGAGCTGGAGCTCTCTTGCATTTGGGGCTTGCCGCCTCCCAGCTCTGCGTTTCTGCAAGCTGATGGCCAGGAGCCAAGCTACGCTGAGGGGCTGTGGGGGCAGTGAGCGTGCCACCCACACAGAGGGACTGAGCGGAAGACGCACACCGCTCCCTTGTCGTGTGGCACAGCTGTGTCACTGCTCTTCTAAACGTGGAGAAAGCCCCTTAAACTCCAAATGGCCAAAGGCTTTGCAGTCCTTGGTTTCACATCCGTGGCACCTTGGGTGGAGTTGCTTCTGTAAGCCAACAGATGAGCAG
Seq C2 exon
GTTGCAGCCCCACCCACGTCACGGTGTACAGCGAGTATGGCGTGGACGTCTTTGATGTGCGCACCATGGAGTGGGTGCAGACCATCGGCCTGCGGAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000198752_CASSETTE2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0078017=CNH=FE(74.8=100)
A:
PF0078017=CNH=PD(0.1=0.0)
C2:
PF0078017=CNH=FE(12.0=100)
Main Inclusion Isoform:
ENST00000361246fB290
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAATGAGATTGTGGCTCCCGG
R:
CCATACTCGCTGTACACCGTG
Band lengths:
348-793
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development