HsaEX0006294 @ hg38
Exon Skipping
Gene
ENSG00000126522 | ASL
Description
argininosuccinate lyase [Source:HGNC Symbol;Acc:HGNC:746]
Coordinates
chr7:66087334-66088921:+
Coord C1 exon
chr7:66087334-66087386
Coord A exon
chr7:66087729-66087791
Coord C2 exon
chr7:66088807-66088921
Length
63 bp
Sequences
Splice sites
3' ss Seq
GCTTCCTCCCACCCCCCCAGAAC
3' ss Score
8.96
5' ss Seq
TGGGTGAGT
5' ss Score
8.73
Exon sequences
Seq C1 exon
TGGGGCCATTGCAGGCAATCCCCTGGGTGTGGACCGAGAGCTGCTCCGAGCAG
Seq A exon
AACTCAACTTTGGGGCCATCACTCTCAACAGCATGGATGCCACTAGTGAGCGGGACTTTGTGG
Seq C2 exon
CCGAGTTCCTGTTCTGGGCTTCGCTGTGCATGACCCATCTCAGCAGGATGGCCGAGGACCTCATCCTCTACTGCACCAAGGAATTCAGCTTCGTGCAGCTCTCAGATGCCTACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000126522_MULTIEX2-8/8=7-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0020615=Lyase_1=PD(0.1=0.0),PF0020615=Lyase_1=FE(16.8=100)
A:
PF0020615=Lyase_1=FE(19.6=100)
C2:
PF0020615=Lyase_1=FE(12.9=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AATCCCCTGGGTGTGGACC
R:
GCTGCACGAAGCTGAATTCCT
Band lengths:
136-199
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development