HsaEX0012031 @ hg38
Exon Skipping
Gene
ENSG00000157445 | CACNA2D3
Description
calcium voltage-gated channel auxiliary subunit alpha2delta 3 [Source:HGNC Symbol;Acc:HGNC:15460]
Coordinates
chr3:54880796-54888052:+
Coord C1 exon
chr3:54880796-54880863
Coord A exon
chr3:54885281-54885326
Coord C2 exon
chr3:54887959-54888052
Length
46 bp
Sequences
Splice sites
3' ss Seq
CCCTTCTCCTTGACCCCCAGGCC
3' ss Score
9.96
5' ss Seq
ATGGTAAGA
5' ss Score
9.48
Exon sequences
Seq C1 exon
TTTAGGTGTGGCGCTTTCCAGAGGTCATGGGAAATATTTCTTCCGAGGGAATGTAACCATCGAAGAAG
Seq A exon
GCCTGCATGACTTAGAACATCCCGATGTGTCCTTGGCAGATGAATG
Seq C2 exon
GTGATAAAGAATTGATCCAAGAAGTCCTTTTTGACGCGGTGGTGAGTGCCCCCATTGAAGCGTATTGGACCAGCCTGGCCCTCAACAAATCTGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157445_MULTIEX7-2/3=C1-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.056 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTTAGGTGTGGCGCTTTCCAG
R:
GGCTGGTCCAATACGCTTCAA
Band lengths:
143-189
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development