HsaEX0012063 @ hg38
Exon Skipping
Gene
ENSG00000167535 | CACNB3
Description
calcium voltage-gated channel auxiliary subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:1403]
Coordinates
chr12:48825660-48828941:+
Coord C1 exon
chr12:48825660-48825769
Coord A exon
chr12:48826367-48826518
Coord C2 exon
chr12:48828662-48828941
Length
152 bp
Sequences
Splice sites
3' ss Seq
GCTGCTGCCTCCCTCCATAGCGG
3' ss Score
9.18
5' ss Seq
AAGGTAAGT
5' ss Score
11
Exon sequences
Seq C1 exon
GATCTCCATCACCCGAGTCACAGCCGACCTCTCCCTGGCAAAGCGATCTGTGCTCAACAATCCGGGCAAGAGGACCATCATTGAGCGCTCCTCTGCCCGCTCCAGCATTG
Seq A exon
CGGAAGTGCAGAGTGAGATCGAGCGCATATTTGAGCTGGCCAAATCCCTGCAGCTAGTAGTGTTGGACGCTGACACCATCAACCACCCAGCACAGCTGGCCAAGACCTCGCTGGCCCCCATCATCGTCTTTGTCAAAGTGTCCTCACCAAAG
Seq C2 exon
AACTTAGGGGGGCCTCCTTGCCTTTCTCATTCTTTTGCCCTGCATCCTGTCATTTCTGTTCTTGTCCCTCATACATCTTTGGAGAACCGGGCTCCAGACTTTGTTCCCTGACTCATAGCTGCCGCTTGTTAGGTTAGGGTTAGATGGGGAGAGACAGGGCACAGAGGACCTGTCTCCCCGGCTACTCTTGCCTTATGGCTCTAGTGTGTGACCTACAGAGCATGCTCCACAAGCCCCTGCCTCACCTCACTGTCATCACTAATAAACATCATGCACAGTC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000167535_MULTIEX2-8/10=7-C2
Average complexity
C3*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.089 A=0.000 C2=0.668
Domain overlap (PFAM):
C1:
PF0062516=Guanylate_kin=PD(31.4=76.2)
A:
PF0062516=Guanylate_kin=FE(27.6=100)
C2:
NO
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTCCATCACCCGAGTCACAG
R:
CCCTAACCTAACAAGCGGCAG
Band lengths:
247-399
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development