HsaEX0014007 @ hg19
Exon Skipping
Gene
ENSG00000101224 | CDC25B
Description
cell division cycle 25 homolog B (S. pombe) [Source:HGNC Symbol;Acc:1726]
Coordinates
chr20:3779059-3780976:+
Coord C1 exon
chr20:3779059-3779110
Coord A exon
chr20:3779520-3779651
Coord C2 exon
chr20:3780935-3780976
Length
132 bp
Sequences
Splice sites
3' ss Seq
AAAACTTTAACTCACTCTAGGCC
3' ss Score
6.24
5' ss Seq
TTGGTGGGC
5' ss Score
3.03
Exon sequences
Seq C1 exon
GTCTCTGCATGGATTCCCCCAGCCCTATGGACCCCCACATGGCGGAGCAGAC
Seq A exon
GCCAAACAAAACACAGTTGCCTGCAGATTGATTTGGCTCTTGGCCGATCAGCAACCTCTGACTTCGATGACACTTTACCCTCTGGCCAGCCCTGGTCTAGGCCCTTTCTGCAAGGGAATGGAGAGAGAGTTG
Seq C2 exon
GTTTGAACAGGCCATCCAGGCAGCCAGCCGGATCATTCGAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000101224-'3-7,'3-6,4-7
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=1.000 C2=0.433
Domain overlap (PFAM):
C1:
PF066178=M-inducer_phosp=PU(33.3=77.8)
A:
NO
C2:
PF066178=M-inducer_phosp=FE(33.3=100)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTCTGCATGGATTCCCCCAG
R:
TTTCGAATGATCCGGCTGGC
Band lengths:
93-225
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)