Special

HsaEX0015639 @ hg19

Exon Skipping

Gene
ENSG00000172243 | CLEC7A
Description
C-type lectin domain family 7, member A [Source:HGNC Symbol;Acc:14558]
Coordinates
chr12:10269402-10278047:-
Coord C1 exon
chr12:10277896-10278047
Coord A exon
chr12:10275844-10275962
Coord C2 exon
chr12:10269402-10271189
Length
119 bp
Sequences
Splice sites
3' ss Seq
TTGTATATGTTTCATTACAGGGA
3' ss Score
8.8
5' ss Seq
CTTGTAAGT
5' ss Score
8
Exon sequences
Seq C1 exon
GGGTTCTTTCCAGCCCTTGTCCTCCTAATTGGATTATATATGAGAAGAGCTGTTATCTATTCAGCATGTCACTAAATTCCTGGGATGGAAGTAAAAGACAATGCTGGCAACTGGGCTCTAATCTCCTAAAGATAGACAGCTCAAATGAATTG
Seq A exon
GGATTTATAGTAAAACAAGTGTCTTCCCAACCTGATAATTCATTTTGGATAGGCCTTTCTCGGCCCCAGACTGAGGTACCATGGCTCTGGGAGGATGGATCAACATTCTCTTCTAACTT
Seq C2 exon
ATTTCAGATCAGAACCACAGCTACCCAAGAAAACCCATCTCCAAATTGTGTATGGATTCACGTGTCAGTCATTTATGACCAACTGTGTAGTGTGCCCTCATATAGTATTTGTGAGAAGAAGTTTTCAATGTAAGAGGAAGGGTGGAGAAGGAGAGAGAAATATGTGAGGTAGTAAGGAGGACAGAAAACAGAACAGAAAAGAGTAACAGCTGAGGTCAAGATAAATGCAGAAAATGTTTAGAGAGCTTGGCCAACTGTAATCTTAACCAAGAAATTGAAGGGAGAGGCTGTGATTTCTGTATTTGTCGACCTACAGGTAGGCTAGTATTATTTTTCTAGTTAGTAGATCCCTAGACATGGAATCAGGGCAGCCAAGCTTGAGTTTTTATTTTTTATTTATTTATTTTTTTGAGATAGGGTCTCACTTTGTTACCCAGGCTGGAGTGCAGTGGCACAATCTCGACTCACTGCAGCTATCTCTCGCCTCAGCCCCTCAAGTA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000172243_MULTIEX1-2/2=C1-C2
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (No Ref, Alt. Stop)





Show structural model

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.007
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0033515=Tetraspannin=PD(35.1=92.2),PF0769011=MFS_1=PD(25.4=56.9),PF083915=Ly49=PD(1.3=2.0),PF059667=Chordopox_A33R=FE(41.0=100)

							
A:
PF0033515=Tetraspannin=PD(2.1=7.5),PF0005916=Lectin_C=FE(36.4=100)

							
C2:
PF0033515=Tetraspannin=PD(2.8=15.4),PF059667=Chordopox_A33R=PD(3.9=19.2)

						

					

				








    
Main Inclusion Isoform:
ENSP00000302569





     
                   









    
Main Skipping Isoform:
ENSP00000431461





     
      









    
Other Inclusion Isoforms:
ENSP00000266456, ENSP00000266456f8438A, ENSP00000379743, ENSP00000432876
          









    
Other Skipping Isoforms:
ENSP00000298523
  



Associated events







Other assemblies


hg38




Conservation


Mouse
(mm10)
chr6:129465455-129465573 
Mouse
(mm9)
chr6:129415473-129415591 
HIGH PSI
MmuEX6007362
(Clec7a)
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr5:100290251-100290369 
HIGH PSI
BtaEX0009212
(CLEC7A)
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GGTTCTTTCCAGCCCTTGTCC

				
R: 
GAGGGCACACTACACAGTTGG

				
Band lengths: 
250-369

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • The Cancer Genome Atlas (TCGA)
  • Genotype-Tissue Expression Project (GTEx)
  • Autistic and control brains
  • Pre-implantation embryo development






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