HsaEX0018270 @ hg38
Exon Skipping
Gene
ENSG00000197408 | CYP2B6
Description
cytochrome P450 family 2 subfamily B member 6 [Source:HGNC Symbol;Acc:HGNC:2615]
Coordinates
chr19:41004297-41009395:+
Coord C1 exon
chr19:41004297-41004446
Coord A exon
chr19:41006905-41007065
Coord C2 exon
chr19:41009219-41009395
Length
161 bp
Sequences
Splice sites
3' ss Seq
GACCTGCTGCTTCTTCCTAGGGG
3' ss Score
8.6
5' ss Seq
CAGGTCAGG
5' ss Score
7.2
Exon sequences
Seq C1 exon
GTGTGATCTTTGCCAATGGAAACCGCTGGAAGGTGCTTCGGCGATTCTCTGTGACCACTATGAGGGACTTCGGGATGGGAAAGCGGAGTGTGGAGGAGCGGATTCAGGAGGAGGCTCAGTGTCTGATAGAGGAGCTTCGGAAATCCAAGG
Seq A exon
GGGCCCTCATGGACCCCACCTTCCTCTTCCAGTCCATTACCGCCAACATCATCTGCTCCATCGTCTTTGGAAAACGATTCCACTACCAAGATCAAGAGTTCCTGAAGATGCTGAACTTGTTCTACCAGACTTTTTCACTCATCAGCTCTGTATTCGGCCAG
Seq C2 exon
CTGTTTGAGCTCTTCTCTGGCTTCTTGAAATACTTTCCTGGGGCACACAGGCAAGTTTACAAAAACCTGCAGGAAATCAATGCTTACATTGGCCACAGTGTGGAGAAGCACCGTGAAACCCTGGACCCCAGCGCCCCCAAGGACCTCATCGACACCTACCTGCTCCACATGGAAAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197408-'7-12,'7-8,10-12
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(57.5=100),PF0006717=p450=PU(1.2=3.9)
A:
PF0006717=p450=FE(11.6=100)
C2:
PF0006717=p450=FE(12.7=100)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AATGGAAACCGCTGGAAGGTG
R:
TTTCACGGTGCTTCTCCACAC
Band lengths:
254-415
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development