HsaEX0018275 @ hg38
Exon Skipping
Gene
ENSG00000100197 | CYP2D6
Description
cytochrome P450 family 2 subfamily D member 6 [Source:HGNC Symbol;Acc:HGNC:2625]
Coordinates
chr22:42128784-42129909:-
Coord C1 exon
chr22:42129738-42129909
Coord A exon
chr22:42129033-42129185
Coord C2 exon
chr22:42128784-42128944
Length
153 bp
Sequences
Splice sites
3' ss Seq
CGTGCCCGTCCCACCCCCAGGGG
3' ss Score
10.64
5' ss Seq
CCGGTGGGT
5' ss Score
7.85
Exon sequences
Seq C1 exon
TTGCGGCGCCGCTTCGGGGACGTGTTCAGCCTGCAGCTGGCCTGGACGCCGGTGGTCGTGCTCAATGGGCTGGCGGCCGTGCGCGAGGCGCTGGTGACCCACGGCGAGGACACCGCCGACCGCCCGCCTGTGCCCATCACCCAGATCCTGGGTTTCGGGCCGCGTTCCCAAG
Seq A exon
GGGTGTTCCTGGCGCGCTATGGGCCCGCGTGGCGCGAGCAGAGGCGCTTCTCCGTGTCCACCTTGCGCAACTTGGGCCTGGGCAAGAAGTCGCTGGAGCAGTGGGTGACCGAGGAGGCCGCCTGCCTTTGTGCCGCCTTCGCCAACCACTCCG
Seq C2 exon
GACGCCCCTTTCGCCCCAACGGTCTCTTGGACAAAGCCGTGAGCAACGTGATCGCCTCCCTCACCTGCGGGCGCCGCTTCGAGTACGACGACCCTCGCTTCCTCAGGCTGCTGGACCTAGCTCAGGAGGGACTGAAGGAGGAGTCGGGCTTTCTGCGCGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100197_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.031 A=0.000 C2=0.007
Domain overlap (PFAM):
C1:
PF0006717=p450=PU(93.4=98.3),PF0006717=p450=PU(4.2=8.6)
A:
PF0006717=p450=FE(11.1=100)
C2:
PF0006717=p450=PD(1.2=1.9),PF0006717=p450=FE(16.1=100)
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCGTGCTCAATGGGCTGG
R:
CTCCTTCAGTCCCTCCTGAGC
Band lengths:
258-411
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development