HsaEX0025367 @ hg38
Exon Skipping
Gene
ENSG00000119402 | FBXW2
Description
F-box and WD repeat domain containing 2 [Source:HGNC Symbol;Acc:HGNC:13608]
Coordinates
chr9:120776093-120778539:-
Coord C1 exon
chr9:120778351-120778539
Coord A exon
chr9:120776931-120777021
Coord C2 exon
chr9:120776093-120776226
Length
91 bp
Sequences
Splice sites
3' ss Seq
AAACTCTGCTCATCCTTTAGGGC
3' ss Score
8.06
5' ss Seq
GAGGTAAAC
5' ss Score
7.2
Exon sequences
Seq C1 exon
ATGACTTGTCTGCAAAGCTGTGGGATGTGAGCACAGGGCAGTGCGTTTATGGCATCCAGACCCACACTTGTGCAGCGGTGAAGTTTGATGAACAGAAGCTTGTGACAGGCTCCTTTGACAACACTGTGGCTTGCTGGGAATGGAGTTCCGGAGCCAGGACCCAGCACTTTCGGGGGCACACGGGGGCGG
Seq A exon
GGCCCATCTCCAATATCGCCTCTTCCCTGAAGTCCTCCCTGATACCCCTGGGCAGAGTTAGTCATTCTCCTTGATGTTTCCCTAGCAAGAG
Seq C2 exon
TATTTAGCGTGGACTACAATGATGAACTGGATATCTTGGTGAGCGGCTCTGCAGACTTCACTGTGAAAGTATGGGCTTTATCTGCTGGGACATGCCTGAACACACTCACCGGGCACACGGAATGGGTCACCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000119402_MULTIEX1-4/6=3-5
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0040027=WD40=PD(28.6=15.2),PF0040027=WD40=WD(100=53.0),PF0040027=WD40=PU(33.3=19.7)
A:
NO
C2:
PF0040027=WD40=PD(64.1=55.6)
Main Inclusion Isoform:
ENST00000608872fB2689
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGACAACACTGTGGCTTGCT
R:
TCAGGCATGTCCCAGCAGATA
Band lengths:
174-265
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development