HsaEX0032354 @ hg38
Exon Skipping
Gene
ENSG00000005884 | ITGA3
Description
integrin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6139]
Coordinates
chr17:50070844-50074004:+
Coord C1 exon
chr17:50070844-50070930
Coord A exon
chr17:50071986-50072182
Coord C2 exon
chr17:50073916-50074004
Length
197 bp
Sequences
Splice sites
3' ss Seq
TTCCCTCCTCTCCTGTGTAGGTG
3' ss Score
11.66
5' ss Seq
AGGGTATGA
5' ss Score
6.84
Exon sequences
Seq C1 exon
GAAACAGCTACATGATTCAGCGCAAGGAGTGGGACTTATCTGAGTATAGTTACAAGGACCCAGAGGACCAAGGAAACCTCTATATTG
Seq A exon
GTGGCAGGACCTCCTGGTGGGCGCCCCCTACTACTTCGAGAGGAAAGAGGAAGTAGGGGGTGCCATCTATGTCTTCATGAACCAGGCGGGAACCTCCTTCCCTGCTCACCCCTCACTCCTTCTTCATGGCCCCAGTGGCTCTGCCTTTGGTTTATCTGTGGCCAGCATTGGTGACATCAACCAGGATGGATTTCAGG
Seq C2 exon
ATATTGCTGTGGGAGCTCCGTTTGAAGGCTTGGGCAAAGTGTACATCTATCACAGTAGCTCTAAGGGGCTCCTTAGACAGCCCCAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000005884_MULTIEX2-2/2=C1-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.025 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF135171=VCBS=FE(88.0=100)
C2:
PF0183918=FG-GAP=PD(70.8=54.8)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACAGCTACATGATTCAGCGCA
R:
CTGCTGGGGCTGTCTAAGGAG
Band lengths:
173-370
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development