HsaEX0032485 @ hg38
Exon Skipping
Gene
ENSG00000139626 | ITGB7
Description
integrin subunit beta 7 [Source:HGNC Symbol;Acc:HGNC:6162]
Coordinates
chr12:53192330-53193363:-
Coord C1 exon
chr12:53193140-53193363
Coord A exon
chr12:53192691-53192910
Coord C2 exon
chr12:53192330-53192538
Length
220 bp
Sequences
Splice sites
3' ss Seq
TCTGCATGGCTCTACCCCAGGCT
3' ss Score
4.88
5' ss Seq
CCGGTGAGG
5' ss Score
9.35
Exon sequences
Seq C1 exon
CTGTGCCCCTGGCCGCCTAGGTCGGCTCTGTGAGTGCTCTGTGGCAGAGCTGTCCTCCCCAGACCTGGAATCTGGGTGCCGGGCTCCCAATGGCACAGGGCCCCTGTGCAGTGGAAAGGGTCACTGTCAATGTGGACGCTGCAGCTGCAGTGGACAGAGCTCTGGGCATCTGTGCGAGTGTGACGATGCCAGCTGTGAGCGACATGAGGGCATCCTCTGCGGAG
Seq A exon
GCTTTGGTCGCTGCCAATGTGGAGTATGTCACTGTCATGCCAACCGCACGGGCAGAGCATGCGAATGCAGTGGGGACATGGACAGTTGCATCAGTCCCGAGGGAGGGCTCTGCAGTGGGCATGGACGCTGCAAATGCAACCGCTGCCAGTGCTTGGACGGCTACTATGGTGCTCTATGCGACCAATGCCCAGGCTGCAAGACACCATGCGAGAGACACCG
Seq C2 exon
GGACTGTGCAGAGTGTGGGGCCTTCAGGACTGGCCCACTGGCCACCAACTGCAGTACAGCTTGTGCCCATACCAATGTGACCCTGGCCTTGGCCCCTATCTTGGATGATGGCTGGTGCAAAGAGCGGACCCTGGACAACCAGCTGTTCTTCTTCTTGGTGGAGGATGACGCCAGAGGCACGGTCGTGCTCAGAGTGAGACCCCAAGAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000139626_MULTIEX1-3/3=2-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.015
Domain overlap (PFAM):
C1:
NO
A:
PF079748=EGF_2=WD(100=51.4)
C2:
PF079657=Integrin_B_tail=FE(87.5=100)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGTGCAGTGGAAAGGGTCAC
R:
GCGTCATCCTCCACCAAGAAG
Band lengths:
292-512
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development