HsaEX0033262 @ hg19
Exon Skipping
Gene
ENSG00000089094 | KDM2B
Description
lysine (K)-specific demethylase 2B [Source:HGNC Symbol;Acc:13610]
Coordinates
chr12:121951079-121958903:-
Coord C1 exon
chr12:121958788-121958903
Coord A exon
chr12:121954272-121954666
Coord C2 exon
chr12:121951079-121951205
Length
395 bp
Sequences
Splice sites
3' ss Seq
TTTTTTTTTTTTTTTTCCAGGAG
3' ss Score
12.13
5' ss Seq
TTTGTAAGT
5' ss Score
7.4
Exon sequences
Seq C1 exon
GTTGGATCCATGCCGTCTACACCCCTGTAGACTCTTTGGTGTTCGGCGGAAACATCCTGCACAGCTTTAACGTGCCCATGCAGCTGCGGATCTACGAGATCGAGGACAGGACGCGG
Seq A exon
GAGAAAAACAAATTGTAGGACACTTCCACCCACTCTCACATTTTGACTTTTTCAAGTCCTTGAGACCTGGGAGTTCTAGATACACTCGAGAAACCTTTTGTTGTCATCTCCTGAGGTCACTCAGCTTGAAGATGACTTGGACCTCCGAGGAAGGGCTGAGGCCAGGTGCCGCTGAGTGGGCCCTGAGGTCCTCTGGTAGACGGATGACCTGCAGGCTGGGAGCATTGCATGCCTTGTGACTGCCTTGCCTTTTGTTTTGGACTGACGTTGGTTAACTCAATTTGGTGAGGCTCCGAGTCTGTCAACAAATAATGTTGAGCAACCGTATGTTTAATGTCCCCAGGCATGTGGCTGAAACCTTTTGAAGGCGAAGGGTGGAAGGCGACAACCTGTTT
Seq C2 exon
GTGCAGCCCAAATTCCGTTACCCCTTCTACTATGAGATGTGCTGGTATGTCCTGGAGAGATACGTGTACTGTGTGACCCAGCGCTCCCACCTCACTCAGGAATACCAGAGGGAGTCGATGCTTATTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000089094_MULTIEX2-2/2=1-C2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.116
Domain overlap (PFAM):
C1:
PF136211=Cupin_8=PD(11.4=59.0)
A:
NO
C2:
PF057817=MRVI1=PU(6.0=11.6)
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGGATCCATGCCGTCTACAC
R:
AAGCATCGACTCCCTCTGGTA
Band lengths:
238-633
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)