HsaEX0034929 @ hg38
Exon Skipping
Gene
ENSG00000188883 | KLRG2
Description
killer cell lectin like receptor G2 [Source:HGNC Symbol;Acc:HGNC:24778]
Coordinates
chr7:139454111-139483712:-
Coord C1 exon
chr7:139483532-139483712
Coord A exon
chr7:139479627-139479772
Coord C2 exon
chr7:139454111-139454214
Length
146 bp
Sequences
Splice sites
3' ss Seq
AGCAGTCTCTGTGCTTGCAGGAG
3' ss Score
6.31
5' ss Seq
CAGGTGAGA
5' ss Score
9.22
Exon sequences
Seq C1 exon
GGAGAGCGAAGCTCCTCTGCACTGGGCCCAGGTGCGCTCCTCAGCGTCTCCGGGTGGCGGGGCGCGCGGGATGGAGGAGTCTTGGGAGGCTGCGCCCGGAGGCCAAGCCGGGGCAGAGCTCCCAATGGAGCCCGTGGGAAGCCTGGTCCCCACGCTGGAGCAGCCGCAGGTGCCCGCGAAG
Seq A exon
GAGCCAGATGCCAGCAGTGCCCCCCAGGCTGGGTGTTGTCCGAGGAGCACTGTTACTACTTCTCTGCAGAAGCGCAGGCCTGGGAAGCCAGCCAGGCTTTCTGCTCAGCCTACCACGCTACCCTCCCCCTGCTAAGCCACACCCAG
Seq C2 exon
GACTTCCTGGGCAGATACCCAGTCTCCAGGCACTCCTGGGTGGGGGCCTGGCGAGGCCCCCAGGGCTGGCACTGGATCGACGAGGCCCCACTCCCGCCCCAGCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000188883_MULTIEX1-2/3=C1-3
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.834 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0005916=Lectin_C=PU(25.8=51.0)
C2:
PF0005916=Lectin_C=FE(35.1=100)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGAAGCTCCTCTGCACTGG
R:
CGTCGATCCAGTGCCAGC
Band lengths:
257-403
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development