HsaEX0036162 @ hg38
Exon Skipping
Gene
ENSG00000115318 | LOXL3
Description
lysyl oxidase like 3 [Source:HGNC Symbol;Acc:HGNC:13869]
Coordinates
chr2:74536291-74549583:-
Coord C1 exon
chr2:74549369-74549583
Coord A exon
chr2:74536709-74536928
Coord C2 exon
chr2:74536291-74536471
Length
220 bp
Sequences
Splice sites
3' ss Seq
CCTCACTCCTGTCCCCCTAGGCT
3' ss Score
10.34
5' ss Seq
GAGGTGTGT
5' ss Score
6.14
Exon sequences
Seq C1 exon
GTAGAGCATCACCTGCAAGTGGAGGAGGTGCGAATTCGACCCGCCGTTGGGTGGGGCAGACGACCCCTGCCCGTGACGGAGGGGCTGGTGGAAGTCAGGCTTCCTGACGGCTGGTCGCAAGTGTGCGACAAAGGCTGGAGCGCCCACAACAGCCACGTGGTCTGCGGGATGCTGGGCTTCCCCAGCGAAAAGAGGGTCAACGCGGCCTTCTACAG
Seq A exon
GCTGCTAGCCCAACGGCAGCAACACTCCTTTGGTCTGCATGGGGTGGCGTGCGTGGGCACGGAGGCCCACCTCTCCCTCTGTTCCCTGGAGTTCTATCGTGCCAATGACACCGCCAGGTGCCCTGGGGGGGGCCCTGCAGTGGTGAGCTGTGTGCCAGGCCCTGTCTACGCGGCATCCAGTGGCCAGAAGAAGCAACAACAGTCGAAGCCTCAGGGGGAG
Seq C2 exon
GCCCGTGTCCGTCTAAAGGGCGGCGCCCACCCTGGAGAGGGCCGGGTAGAAGTCCTGAAGGCCAGCACATGGGGCACAGTCTGTGACCGCAAGTGGGACCTGCATGCAGCCAGCGTGGTGTGTCGGGAGCTGGGCTTCGGGAGTGCTCGAGAAGCTCTGAGTGGCGCTCGCATGGGGCAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115318_MULTIEX1-2/8=1-3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.025 A=0.174 C2=0.120
Domain overlap (PFAM):
C1:
PF0053013=SRCR=PU(48.5=68.1)
A:
PF0053013=SRCR=PD(50.5=68.9)
C2:
PF0053013=SRCR=PU(67.9=90.2),PF0118612=Lysyl_oxidase=PU(23.9=44.3)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAAGTGGAGGAGGTGCGAATT
R:
CCACTTGCGGTCACAGACTG
Band lengths:
296-516
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development