HsaEX0038607 @ hg38
Exon Skipping
Gene
ENSG00000175221 | MED16
Description
mediator complex subunit 16 [Source:HGNC Symbol;Acc:HGNC:17556]
Coordinates
chr19:871037-873582:-
Coord C1 exon
chr19:873449-873582
Coord A exon
chr19:871926-872118
Coord C2 exon
chr19:871037-871253
Length
193 bp
Sequences
Splice sites
3' ss Seq
CCGATGCCTCTTTCGGGCAGGGT
3' ss Score
6.34
5' ss Seq
GCTGTGAGG
5' ss Score
2.85
Exon sequences
Seq C1 exon
ACATTGACAAGGTCATGATCAACCTCAAGACGGAGGAATTTGTGCTGGACATGAACACACTGCAGGCGCTGCAGCAGCTCTTGCAGTGGGTGGGCGACTTCGTGCTGTACCTGCTGGCCAGCCTACCCAACCAG
Seq A exon
GGTTCCCTGCTGAGGCCGGGCCACAGCTTTCTGCGGGACGGCACCTCGCTGGGCATGCTTCGGGAATTGATGGTGGTCATCCGCATCTGGGGCCTTCTGAAGCCCAGCTGCCTGCCCGTGTATACGGCCACCTCGGATACCCAGGACAGCATGTCCCTGCTCTTCCGCCTGCTCACCAAGCTCTGGATCTGCT
Seq C2 exon
GTCGCGATGAGGGCCCAGCGAGCGAGCCGGACGAGGCGCTGGTGGATGAATGCTGCCTGCTGCCCAGCCAGCTGCTTATCCCCAGCCTGGACTGGCTGCCAGCCAGCGACGGCCTGGTTAGCCGCCTGCAGCCCAAGCAGCCCCTTCGTCTGCAGTTTGGCCGGGCGCCCACGCTGCCTGGCAGTGCTGCCACCCTGCAGCTCGACGGCCTCGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175221_MULTIEX1-13/15=11-15
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.043
Domain overlap (PFAM):
C1:
PF116353=Med16=FE(10.8=100)
A:
PF116353=Med16=FE(8.7=100)
C2:
PF116353=Med16=PU(10.1=70.0)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGACATGAACACACTGCAGG
R:
CCAAACTGCAGACGAAGGGG
Band lengths:
249-442
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development