HsaEX0039544 @ hg19
Exon Skipping
Gene
ENSG00000078403 | MLLT10
Description
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 [Source:HGNC Symbol;Acc:16063]
Coordinates
chr10:22024068-22029082:+
Coord C1 exon
chr10:22024068-22024164
Coord A exon
chr10:22027343-22027489
Coord C2 exon
chr10:22028959-22029082
Length
147 bp
Sequences
Splice sites
3' ss Seq
TCTAATAATAGCATGTGTAGCTG
3' ss Score
-3.58
5' ss Seq
TAGGTGAGG
5' ss Score
7.65
Exon sequences
Seq C1 exon
TGCCTCAGGACTAGGATTACTTTCTGACCAGCAACGACAAATACTTATTCATCAACAGCAGTTTCAGCAGTTGTTAAATTCTCAACAGCTCACACCA
Seq A exon
CTGTCTCATTTCCAGAACATGGTTAAGGAATTTTCAGCACAAATTATTGCTTGGAGACCATGAGGACTAAAGGACTGTACTTTTTCCTTCATCTGCCAATGTCGTGGGCTAAAGTTTGTTCATTTACAGGGATCAAACTTAACGTAG
Seq C2 exon
GAACAACATCAAGCCTTTTTGTATCAGTTAATGCAACATCACCACCAGCAGCACCACCAACCTGAACTTCAGCAGCTGCAGATCCCTGGACCAACACAAATACCCATAAACAACCTTCTTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078403_MULTIEX2-1/3=C1-2
Average complexity
C1*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.293 A=0.000 C2=0.957
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCCTCAGGACTAGGATTACT
R:
TGCAAGAAGGTTGTTTATGGGT
Band lengths:
220-367
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)