HsaEX0039544 @ hg38
Exon Skipping
Gene
ENSG00000078403 | MLLT10
Description
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 [Source:HGNC Symbol;Acc:HGNC:16063]
Coordinates
chr10:21735139-21740236:+
Coord C1 exon
chr10:21735139-21735235
Coord A exon
chr10:21738429-21738560
Coord C2 exon
chr10:21740030-21740236
Length
132 bp
Sequences
Splice sites
3' ss Seq
TGTAGCTGTCTCATTTCCAGAAC
3' ss Score
8.78
5' ss Seq
TAGGTGAGG
5' ss Score
7.65
Exon sequences
Seq C1 exon
TGCCTCAGGACTAGGATTACTTTCTGACCAGCAACGACAAATACTTATTCATCAACAGCAGTTTCAGCAGTTGTTAAATTCTCAACAGCTCACACCA
Seq A exon
AACATGGTTAAGGAATTTTCAGCACAAATTATTGCTTGGAGACCATGAGGACTAAAGGACTGTACTTTTTCCTTCATCTGCCAATGTCGTGGGCTAAAGTTTGTTCATTTACAGGGATCAAACTTAACGTAG
Seq C2 exon
GAACAACATCAAGCCTTTTTGTATCAGTTAATGCAACATCACCACCAGCAGCACCACCAACCTGAACTTCAGCAGCTGCAGATCCCTGGACCAACACAAATACCCATAAACAACCTTCTTGCAGGTACACAGGCACCCCCACTTCACACAGCTACCACCAACCCATTTCTCACCATCCATGGAGATAATGCAAGTCAGAAAGTAGCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078403_MULTIEX2-1/3=C1-2
Average complexity
C1*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.279 A=0.000 C2=0.957
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
ENST00000307729fB4333
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTTTCTGACCAGCAACGACA
R:
AATGGGTTGGTGGTAGCTGTG
Band lengths:
246-378
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development