HsaEX0042543 @ hg38
Exon Skipping
Gene
ENSG00000119408 | NEK6
Description
NIMA related kinase 6 [Source:HGNC Symbol;Acc:HGNC:7749]
Coordinates
chr9:124257963-124302054:+
Coord C1 exon
chr9:124257963-124258085
Coord A exon
chr9:124292849-124293013
Coord C2 exon
chr9:124301936-124302054
Length
165 bp
Sequences
Splice sites
3' ss Seq
AGGACATTTCCATGTTCAAGGAG
3' ss Score
2.31
5' ss Seq
GAGGTGAGA
5' ss Score
7.66
Exon sequences
Seq C1 exon
GGCGGAACCGAGCTGACGGGCGTGCGGCCGCTGCGCCGCAAACTCGTGTGGGACGCACCGCTCCAGCCGCCCGCGGGCCAGCGCACCGGTCCCCCAGCGGCAGCCGAGCCCGCCCGCGCGCCG
Seq A exon
GAGAAGAAGACACATGAATTAGAGACAGCACGGGGGAGCAGGCTGTGGAGCTGGGAGTGACGGGGTGAGTCCAGGAAGGCTGCCTGGAGGAGATGCCCAGGAGAGAAGTTTGCTGGGAGGCAGCTCATTTCCGGCAGGAGGAGCAGAGCCTGCCAAGGCCTCGAG
Seq C2 exon
TTCGTGCCCTCGTGAGGCTGGCATGCAGGATGGCAGGACAGCCCGGCCACATGCCCCATGGAGGGAGTTCCAACAACCTCTGCCACACCCTGGGGCCTGTGCATCCTCCTGACCCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000119408_MULTIEX1-2/7=C1-3
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. ATG)
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.000 C2=0.810
Domain overlap (PFAM):
C1:
NA
A:
NO
C2:
PF0006920=Pkinase=PU(0.6=3.3)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGCGCCGCAAACTCGTG
R:
CTGTGGGTCAGGAGGATGCA
Band lengths:
212-377
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development