HsaEX0052377 @ hg19
Exon Skipping
Gene
ENSG00000170667 | RASA4B
Description
RAS p21 protein activator 4B [Source:HGNC Symbol;Acc:35202]
Coordinates
chr7:102136916-102141240:-
Coord C1 exon
chr7:102141146-102141240
Coord A exon
chr7:102137294-102137411
Coord C2 exon
chr7:102136916-102137066
Length
118 bp
Sequences
Splice sites
3' ss Seq
TCACAGGCTGCCCATTCCAGGGG
3' ss Score
4.63
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
Exon sequences
Seq C1 exon
GTGGTGATTGATGTCCAGAGACTGCGGGTGGTGCAGCAGGAGGAGGGCTGGTTCCGGCTGCAGCCCGACCAGTCCAAGAGCCGGCGGCATGACGA
Seq A exon
GGGCAACCTGGGCTCCTTGCAGCTGGAGGTGCGGCTGCGGGACGAGACGGTGCTGCCCTCCAGCTACTACCAGCCACTGGTGCACCTGCTGTGCCACGAGGTCAAGCTGGGCATGCAG
Seq C2 exon
GGCCCAGGGCAGCTGATCCCACTCATCGAGGAGACAACCAGCACCGAGTGTCGCCAGGACGTGGCCACGAACCTGCTCAAGCTCTTCCTGGGGCAGGGGCTGGCCAAGGACTTCCTGGACCTGCTCTTCCAGCTGGAGCTGAGTCGCACCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000170667_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.188 A=0.025 C2=0.000
Domain overlap (PFAM):
C1:
PF0016825=C2=PD(1.2=3.1)
A:
NO
C2:
PF0061614=RasGAP=PU(6.8=25.5)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGTGATTGATGTCCAGAGACTGC
R:
GTGCGACTCAGCTCCAGC
Band lengths:
242-360
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)