HsaEX0052784 @ hg19
Exon Skipping
Gene
ENSG00000076067 | RBMS2
Description
RNA binding motif, single stranded interacting protein 2 [Source:HGNC Symbol;Acc:9909]
Coordinates
chr12:56956201-56963774:+
Coord C1 exon
chr12:56956201-56956367
Coord A exon
chr12:56961850-56961970
Coord C2 exon
chr12:56963683-56963774
Length
121 bp
Sequences
Splice sites
3' ss Seq
ATCCTATCTCCATTTTACAGATG
3' ss Score
9.64
5' ss Seq
GGGGTCAGT
5' ss Score
3.99
Exon sequences
Seq C1 exon
CCATATGTGTCATTGGCTCAGCAGATGGCACCACCTAGCCCAAGCAACAGTACACCTAACAGCAGTAGTGGAAGCAATGGAAATGACCAGCTGAGCAAAACCAACCTATACATCCGAGGATTGCAACCAGGCACTACTGACCAAGATCTTGTCAAGCTGTGTCAGCC
Seq A exon
ATGATGAGGCTGAGACACCAAAAGGTTCAATGACTTGTTCAAGATCACGCATAGCTAAAAAGTGGCAGAACCAGGATTTGAACCAAAGCAATTTGGCTCAGGTTGACCTTCAATTAAAGGG
Seq C2 exon
GCTATGGCTTTGTAGATTTTGACAGCCCTTCAGCAGCACAGAAAGCTGTAACAGCACTGAAGGCCAGCGGTGTACAGGCACAGATGGCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000076067_MULTIEX1-3/5=2-5
Average complexity
C2
Mappability confidence:
92%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.742 A=1.000 C2=0.290
Domain overlap (PFAM):
C1:
PF0007617=RRM_1=PU(29.9=35.7)
A:
NO
C2:
PF0007617=RRM_1=PD(38.8=83.9)
Other Inclusion Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTCATTGGCTCAGCAGATGG
R:
TTGCCATCTGTGCCTGTACAC
Band lengths:
250-371
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)