HsaEX0053091 @ hg38
Exon Skipping
Gene
ENSG00000084093 | REST
Description
RE1 silencing transcription factor [Source:HGNC Symbol;Acc:HGNC:9966]
Coordinates
chr4:56907876-56919870:+
Coord C1 exon
chr4:56907876-56908213
Coord A exon
chr4:56910630-56911536
Coord C2 exon
chr4:56919787-56919870
Length
907 bp
Sequences
Splice sites
3' ss Seq
TTGTTTTGTTTTTAATTCAGAAT
3' ss Score
7.72
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
Exon sequences
Seq C1 exon
GGCGGCGGCGGCGGCGCGGACTGGGTGCGCGGCGCAGCGTCCTGTGTTGGAATGTGCGGCTGCCGCGAGCTCGCGGCGCAGCAGCGGAGCGAGCGCCGCCGAGGCCCGGGGCCCCAGACCCTGGCGGCGGCTGCCGCAGCCGAGACGGCAGGGCGAGGCCCGGAGGCCTGAGCACCCTCTGCAGCCCCACTCCTGGGCCTTCTTGGTCCACGACGGCCCCAGCACCCAACTTTACCACCCTCCCCCACCTCTCCCCCGAAACTCCAGCAACAAAGAAAAGTAGTCGGAGAAGGAGCGGCGACTCAGGGTCGCCCGCCCCTCCTCACCGAGGAAGGCCG
Seq A exon
AATACAGTTATGGCCACCCAGGTAATGGGGCAGTCTTCTGGAGGAGGAGGGCTGTTTACCAGCAGTGGCAACATTGGAATGGCCCTGCCTAACGACATGTATGACTTGCATGACCTTTCCAAAGCTGAACTGGCCGCACCTCAGCTTATTATGCTGGCAAATGTGGCCTTAACTGGGGAAGTAAATGGCAGCTGCTGTGATTACCTGGTCGGTGAAGAAAGACAGATGGCAGAACTGATGCCGGTTGGGGATAACAACTTTTCAGATAGTGAAGAAGGAGAAGGACTTGAAGAGTCTGCTGATATAAAAGGTGAACCTCATGGACTGGAAAACATGGAACTGAGAAGTTTGGAACTCAGCGTCGTAGAACCTCAGCCTGTATTTGAGGCATCAGGTGCTCCAGATATTTACAGTTCAAATAAAGATCTTCCCCCTGAAACACCTGGAGCGGAGGACAAAGGCAAGAGCTCGAAGACCAAACCCTTTCGCTGTAAGCCATGCCAATATGAAGCAGAATCTGAAGAACAGTTTGTGCATCACATCAGAGTTCACAGTGCTAAGAAATTTTTTGTGGAAGAGAGTGCAGAGAAGCAGGCAAAAGCCAGGGAATCTGGCTCTTCCACTGCAGAAGAGGGAGATTTCTCCAAGGGCCCCATTCGCTGTGACCGCTGCGGCTACAATACTAATCGATATGATCACTATACAGCACACCTGAAACACCACACCAGAGCTGGGGATAATGAGCGAGTCTACAAGTGTATCATTTGCACATACACAACAGTGAGCGAGTATCACTGGAGGAAACATTTAAGAAACCATTTTCCAAGGAAAGTATACACATGTGGAAAATGCAACTATTTTTCAGACAGAAAAAACAATTATGTTCAGCATGTTAGAACTCATACAG
Seq C2 exon
GAGAACGCCCATATAAATGTGAACTTTGTCCTTACTCAAGTTCTCAGAAGACTCATCTAACTAGACATATGCGTACTCATTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000084093-'0-12,'0-3,11-12
Average complexity
C1
Mappability confidence:
87%=100=75%
Protein Impact
ORF disruption upon sequence exclusion (Ref, Alt. ATG (<=10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.341 C2=0.141
Domain overlap (PFAM):
C1:
NA
A:
PF134651=zf-H2C2_2=WD(100=10.0),PF134651=zf-H2C2_2=WD(100=8.7),PF134651=zf-H2C2_2=PU(38.5=3.3)
C2:
PF134651=zf-H2C2_2=PD(57.7=51.7),PF134651=zf-H2C2_2=PU(38.5=34.5)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCGTCCTGTGTTGGAATGTG
R:
ACTTGAGTAAGGACAAAGTTCACA
Band lengths:
344-1251
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development