HsaEX0057917 @ hg19
Exon Skipping
Gene
ENSG00000125731 | SH2D3A
Description
SH2 domain containing 3A [Source:HGNC Symbol;Acc:16885]
Coordinates
chr19:6754063-6754742:-
Coord C1 exon
chr19:6754627-6754742
Coord A exon
chr19:6754262-6754436
Coord C2 exon
chr19:6754063-6754174
Length
175 bp
Sequences
Splice sites
3' ss Seq
CTTGCCCTCCACCTCTGCAGGCA
3' ss Score
9.79
5' ss Seq
CAGGTTCGT
5' ss Score
7.97
Exon sequences
Seq C1 exon
GCCACAGGCCTCCTGGGAGTGACCAGAGATCAGCGGGGCAACATGGGAGTCTCATCTGGCCTGGAGCTGCTCACTCTTCCCCATGGACACCACTTGAGGTTGGAACTGCTGGAGAG
Seq A exon
GCATCAGACACTGGCGCTGGCCGGGGCGCTGGCGGTGCTGGGCTGCTCGGGGCCGCTGGAGGAGCGCGCAGCCGCACTGAGGGGACTGGTAGAGCTGGCGCTGGCGCTGCGGCCAGGGGCGGCGGGGGACCTGCCCGGGCTGGCTGCAGTCATGGGCGCCCTGCTCATGCCCCAG
Seq C2 exon
GTGTCCCGGTTGGAGCACACGTGGCGCCAGCTCCGAAGGAGCCACACGGAGGCTGCGCTGGCCTTTGAGCAGGAGCTGAAGCCGCTGATGCGGGCTCTGGATGAGGGCGCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125731-'5-6,'5-5,6-6
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.115 A=0.040 C2=0.100
Domain overlap (PFAM):
C1:
PF0061714=RasGEF=PU(7.5=23.1)
A:
PF0061714=RasGEF=FE(48.3=100)
C2:
PF0061714=RasGEF=FE(30.8=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCTCCTGGGAGTGACCA
R:
AGCGCCCTCATCCAGAGC
Band lengths:
220-395
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)