HsaEX0057920 @ hg38
Exon Skipping
Gene
ENSG00000125731 | SH2D3A
Description
SH2 domain containing 3A [Source:HGNC Symbol;Acc:HGNC:16885]
Coordinates
chr19:6759594-6763816:-
Coord C1 exon
chr19:6763705-6763816
Coord A exon
chr19:6760638-6760987
Coord C2 exon
chr19:6759594-6759670
Length
350 bp
Sequences
Splice sites
3' ss Seq
CCCCTGAACTTCATCCACAGAAG
3' ss Score
7.85
5' ss Seq
CAGGTACTC
5' ss Score
7.04
Exon sequences
Seq C1 exon
ATGTGGAAGACTGAGGCCTGTTGAAAGTGCAGAGCTCAGCCCTGGCACCCTCTGTTCCCAAGAGCTCCATGCAGGTGCCACAGGATGGAGAAGACCTTGCTGGCCAACCTTG
Seq A exon
AAGGCTGAAGCTCTTCTTCAGCAAAATGGCGACTTCCTGGTTCGCGCCTCTGGGTCCCGTGGGGGCAACCCCGTGATCTCCTGCCGCTGGCGGGGCTCAGCCCTCCATTTTGAGGTGTTCCGTGTGGCCCTGCGTCCCCGGCCAGGCCGACCCACAGCCCTCTTTCAACTGGAGGATGAGCAATTCCCCAGCATACCGGCTCTGGTTCACAGTTATATGACAGGCAGGCGCCCACTGTCCCAGGCCACAGGGGCTGTGGTCTCCAGGCCTGTGACTTGGCAGGGGCCTCTGCGACGCAGCTTTAGCGAGGACACCCTGATGGATGGCCCAGCTCGGATAGAGCCTCTCAG
Seq C2 exon
GGCAAGGAAGTGGAGCAACAGTCAGCCTGCAGATTTGGCACATATGGGGCGGTCAAGAGAAGACCCCGCTGGGATGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125731_MULTIEX2-2/4=1-3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.422 A=0.325 C2=1.000
Domain overlap (PFAM):
C1:
PF0001719=SH2=PU(9.9=34.8)
A:
PF0001719=SH2=PD(87.7=60.7)
C2:
NO
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGTGGAAGACTGAGGCCTGT
R:
CCAGCGGGGTCTTCTCTTGA
Band lengths:
184-534
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development