HsaEX0065117 @ hg38
Exon Skipping
Gene
ENSG00000198586 | TLK1
Description
tousled like kinase 1 [Source:HGNC Symbol;Acc:HGNC:11841]
Coordinates
chr2:171014851-171028405:-
Coord C1 exon
chr2:171028339-171028405
Coord A exon
chr2:171022872-171023129
Coord C2 exon
chr2:171014851-171014948
Length
258 bp
Sequences
Splice sites
3' ss Seq
CTTGTGCCTCCGTTCTGAAGAGA
3' ss Score
4.72
5' ss Seq
TAGGTGAAT
5' ss Score
3.81
Exon sequences
Seq C1 exon
GTTGACTTTGGCAGAATATCATGAACAGGAAGAAATTTTCAAACTTAGACTAGGACATCTCAAAAAG
Seq A exon
AGATAACAGTATAGCAACAACTCTGCCACTGAAATCCTGTTCTCTGACCGATATTGGCACCTGCAAAGAGAAACAACCAGTAACAGGCAGCAGCAGCATCAGTATTAATCTTCCATGATGAAATCTTTACAGGTCAAGAACAAGTACACAGCTCTTTTCTCACTCCTTCACAGTGGACCATGCAACTAGTTGAAATGGAAGACAATGGATTGTCTACAAGCCTTTTGAACAGTGGAGAATGCAGGGCGTTGGCTTTAG
Seq C2 exon
GAAGAGGCAGAAATCCAGGCAGAACTTGAACGTTTGGAAAGAGTCAGAAATCTTCACATACGTGAGCTGAAAAGAATAAACAATGAAGATAATTCACA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000198586_MULTIEX3-11/11=10-C2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.029 A=0.000 C2=0.182
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTTTGGCAGAATATCATGAACAGGA
R:
CATTGTTTATTCTTTTCAGCTCACGT
Band lengths:
148-406
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development