HsaEX0066843 @ hg19

Exon Skipping

Gene

ENSG00000082512 | TRAF5

Description

TNF receptor-associated factor 5 [Source:HGNC Symbol;Acc:12035]

Coordinates

chr1:211538718-211542934:+

Coord C1 exon

chr1:211538718-211538810

Coord A exon

chr1:211539733-211539832

Coord C2 exon

chr1:211542794-211542934

Length

100 bp

Sequences

Splice sites

3' ss Seq

CATCCATCTTTTCATTCAAGAAA

3' ss Score

5.17

5' ss Seq

CAGGTAAGT

5' ss Score

10.86

Exon sequences

Seq C1 exon

GATAAACGGAGGAACCTGCAGCAACATGAGCATTCAGCCTTACGGGAGCACATGCGTTTGGTTTTAGAAAAGAATGTCCAATTAGAAGAACAG

Seq A exon

AAACACCTACTGTATGTCAGGTACAATGTTTGCTGCTAGGGACACTGAGCCAAGGAAGATGTAGCCTCTACCCTTGAAGAACTAACATAAATGTAAACAG

Seq C2 exon

ATTTCTGACTTACACAAGAGCCTAGAACAGAAAGAAAGTAAAATCCAGCAGCTAGCAGAAACTATAAAGAAACTTGAAAAGGAGTTCAAGCAGTTTGCACAGTTGTTTGGCAAAAATGGAAGCTTCCTCCCAAACATCCAG

VastDB Features

Vast-tools module Information

Secondary ID

ENSG00000082512_MULTIEX1-9/11=8-10

Average complexity

S*

Mappability confidence:

100%=100=100%

Protein Impact

ORF disruption upon sequence inclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.091 A=0.000 C2=0.000

Domain overlap (PFAM):

C1:

PF0217613=zf-TRAF=PD(13.6=25.8),PF059116=DUF869=FE(11.5=100),PF086146=ATG16=FE(40.5=100),PF100464=BLOC1_2=PU(18.4=58.1)

A:

NO

C2:

PF059116=DUF869=FE(17.6=100),PF086146=ATG16=PD(47.3=74.5),PF100464=BLOC1_2=FE(46.9=100)

Main Inclusion Isoform:

ENSP00000261464f1364A

Main Skipping Isoform:

ENSP00000261464

Other Inclusion Isoforms:

NA

Other Skipping Isoforms:

ENSP00000336825, ENSP00000355971, ENSP00000389891

Associated events

HsaINT0171757

Other assemblies

hg38

Conservation

Mouse

(mm10)

chr1:192053510-192053587

Mouse

(mm9)

chr1:193877391-193877468

Rat

(rn6)

No conservation detected

Cow

(bosTau6)

chr16:73901719-73901818

Chicken

(galGal4)

No conservation detected

Chicken

(galGal3)

No conservation detected

Zebrafish

(danRer10)

No conservation detected

Fruitfly

(dm6)

No conservation detected

Primers PCR

Suggestions for RT-PCR validation

F:

GATAAACGGAGGAACCTGCAGC

R:

CTGGATGTTTGGGAGGAAGCT

Band lengths:

234-334

Functional annotations

(Submit an annotation)

There are 0 annotated functions for this event

GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]

SPECIAL DATASETS

The Cancer Genome Atlas (TCGA)
Genotype-Tissue Expression Project (GTEx)
Autistic and control brains
Pre-implantation embryo development

Other AS DBs:

FasterDB (Includes CLIP-seq data)

AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)

APPRIS (Selection of principal isoform)

DEU primates (Only for human)

Special

HsaEX0066843 @ hg19

GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]

SPECIAL DATASETS